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1. (WO2001004326) TANKYRASE HOMOLOG PROTEIN (THP), NUCLEIC ACIDS, AND METHODS RELATED TO THE SAME

Pub. No.:    WO/2001/004326    International Application No.:    PCT/EP2000/006609
Publication Date: Fri Jan 19 00:59:59 CET 2001 International Filing Date: Tue Jul 04 01:59:59 CEST 2000
IPC: A61K 38/00
C12N 9/10
Applicants: PHARMACIA ITALIA S.P.A.
BERTHELSEN, Jens
TOMA, Salvatore
ISACCHI, Antonella
Inventors: BERTHELSEN, Jens
TOMA, Salvatore
ISACCHI, Antonella
Title: TANKYRASE HOMOLOG PROTEIN (THP), NUCLEIC ACIDS, AND METHODS RELATED TO THE SAME
Abstract:
The present invention provides a human polypeptide homolog of human tankyrase protein (THP) and polynucleotides which identify and encode THP. In addition, the invention provides expression vectors, host cells and methods for its production. The invention also provides methods for the identification of THP agonists/antagonists, useful for the treatment of human diseases, such as human cancer and age related diseases.