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Machine translation
1. (WO2001004306) EXPRESSION VECTORS AND METHODS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2001/004306    International Application No.:    PCT/US2000/018841
Publication Date: 18.01.2001 International Filing Date: 11.07.2000
Chapter 2 Demand Filed:    15.01.2001    
IPC:
C07K 14/435 (2006.01), C07K 14/71 (2006.01), C07K 16/42 (2006.01), C12N 15/10 (2006.01), C12N 15/65 (2006.01), C12N 15/69 (2006.01), C12N 15/85 (2006.01)
Applicants: GENENTECH, INC. [US/US]; 1 DNA Way, South San Francisco, CA 94080-4990 (US) (For All Designated States Except US).
CHISHOLM, Vanessa [US/US]; (US) (For US Only).
CROWLEY, Craig, W. [US/US]; (US) (For US Only).
KRUMMEN, Lynne, A. [US/US]; (US) (For US Only).
MENG, Yu-Ju, G. [US/US]; (US) (For US Only)
Inventors: CHISHOLM, Vanessa; (US).
CROWLEY, Craig, W.; (US).
KRUMMEN, Lynne, A.; (US).
MENG, Yu-Ju, G.; (US)
Agent: TAN, Lee, K.; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080-4990 (US).
WALTON, Sean, M.; Mewburn Ellis, York House, 23 Kingsway, London WC2B 6HP (GB)
Priority Data:
60/143,360 12.07.1999 US
Title (EN) EXPRESSION VECTORS AND METHODS
(FR) VECTEURS D'EXPRESSION ET PROCEDES
Abstract: front page image
(EN)Vectors and methods for efficient isolation of recombinant cells expressing high levels of a desired protein are provided. The vectors comprise an amplifiable selectable gene, a fluorescent protein gene, and a gene encoding a desired product in a manner that optimizes transcriptional and translational linkage.
(FR)La présente invention concerne des vecteurs et des procédés destinés à une isoler efficacement des cellules recombinantes exprimant des niveaux élevés d'une protéine recherchée. Les vecteurs comprennent un gène amplifiable que l'on peut sélectionner, un gène de protéine fluorescente et un gène codant pour un produit recherché d'une manière qui optimise un couplage de transcription et de translation.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)