WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2001003740) SERINE PROTEASE INHIBITOR
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2001/003740    International Application No.:    PCT/JP2000/004595
Publication Date: 18.01.2001 International Filing Date: 10.07.2000
Chapter 2 Demand Filed:    23.01.2001    
IPC:
A61K 38/00 (2006.01), A61K 38/55 (2006.01), C07K 14/81 (2006.01), C12N 9/64 (2006.01)
Applicants: FUJIMORI KOGYO CO., LTD. [JP/JP]; 4-16, Nihonbashibakurocho 1-chome, Chuo-ku, Tokyo 103-0002 (JP) (For All Designated States Except US).
CHISSO CORPORATION [JP/JP]; 6-32, Nakanoshima 3-chome, Kita-ku, Osaka-shi, Osaka 530-0005 (JP) (For All Designated States Except US).
SHIMA, Midori [JP/JP]; (JP) (For US Only).
KOIDE, Takehiko [JP/JP]; (JP) (For US Only).
HOSOKAWA, Kazuya [JP/JP]; (JP) (For US Only).
SUZUKI, Toyoaki [JP/JP]; (JP) (For US Only).
NAGATA, Masanori [JP/JP]; (JP) (For US Only)
Inventors: SHIMA, Midori; (JP).
KOIDE, Takehiko; (JP).
HOSOKAWA, Kazuya; (JP).
SUZUKI, Toyoaki; (JP).
NAGATA, Masanori; (JP)
Agent: HATTA, Mikio; Dia Palace Nibancho, 11-9, Nibancho, Chiyoda-ku, Tokyo 102-0084 (JP)
Priority Data:
11/194622 08.07.1999 JP
2000/25341 02.02.2000 JP
2000/34169 10.02.2000 JP
Title (EN) SERINE PROTEASE INHIBITOR
(FR) INHIBITEUR DE LA SERINE PROTEASE
Abstract: front page image
(EN)A serine protease inhibitor capable of selectively inhibiting the target serine protease activity alone. This serine protease inhibitor binds to the substrate of serine protease competitively with the serine protease to thereby inhibit the reaction between the serine protease and the substrate. This inhibitor specifically binds to the substrate of the target serine protease to thereby inhibit the activity of the serine protease. This serine protease inhibitor is useful as an antithrombotic agent, a fibrinolysin inhibitor, an anti-digestive enzyme agent and a remedy for disseminated intravascular coagulation.
(FR)L'invention concerne un inhibiteur de la sérine protéase, capable d'inhiber sélectivement seulement l'activité de la sérine protéase cible. Ledit inhibiteur de la sérine protéase se fixe au substrat de la sérine protéase en compétition avec la sérine protéase, de manière qu'il inhibe la réaction entre la sérine protéase et le substrat. Ledit inhibiteur se fixe spécifiquement au substrat de la sérine protéase cible, de manière qu'il inhibe l'activité de la sérine protéase. Il est utile en tant qu'agent antithrombotique, en tant qu'inhibiteur de la fibrolysine, en tant qu'agent enzymatique anti-digestif et en tant que remède contre la coagulation intravasculaire disséminée.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)