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Machine translation
1. (WO2001003728) GENE THERAPY FOR ENHANCING AND/OR INDUCING ANGIOGENESIS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2001/003728    International Application No.:    PCT/NL2000/000482
Publication Date: 18.01.2001 International Filing Date: 07.07.2000
Chapter 2 Demand Filed:    08.02.2001    
IPC:
A61K 38/44 (2006.01), A61K 48/00 (2006.01)
Applicants: Crucell Holland B.V. [NL/NL]; Archimedesweg 4, NL-2333 CN Leiden (NL) (For All Designated States Except US).
VOGELS, Ronald [NL/NL]; (NL) (For US Only).
VERLINDEN, Stefan, Frederik, Franciscus [NL/NL]; (NL) (For US Only)
Inventors: VOGELS, Ronald; (NL).
VERLINDEN, Stefan, Frederik, Franciscus; (NL)
Agent: CRUCELL HOLLAND B.V.; Intellectual Property Department, Postbus 2048, NL-2301 CA Leiden (NL)
Priority Data:
60/143,101 09.07.1999 US
99202263.2 09.07.1999 EP
Title (EN) GENE THERAPY FOR ENHANCING AND/OR INDUCING ANGIOGENESIS
(FR) THERAPIE GENIQUE DESTINEE AU RENFORCEMENT ET/OU A L'INDUCTION DE L'ANGIOGENESE
Abstract: front page image
(EN)The invention relates to gene therapy for enhancing and/or inducing angiogenesis, wherein use is made of a nucleic acid sequence encoding Nitric Oxide Synthase (NOS). In particular, the nucleic acid sequence is administered in a systemic treatment, preferably comprising isolated tissue perfusion.
(FR)La présente invention se rapporte à une thérapie génique destinée au renforcement et/ou à l'induction de l'angiogenèse et consistant à utiliser une séquence d'acides nucléiques codant pour la monoxyde-d'azote synthase (NOS). L'invention se rapporte particulièrement à l'administration d'une telle séquence d'acides nucléiques au cours d'un traitement systémique comprenant, de préférence, une irrigation de tissus isolés.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)