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1. (WO2001003722) CFTR POLYPEPTIDES, FRAGMENTS THEREOF AND METHODS OF USE TO OVERCOME BIOSYNTHETIC MISPROCESSING
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2001/003722 International Application No.: PCT/US2000/040324
Publication Date: 18.01.2001 International Filing Date: 07.07.2000
Chapter 2 Demand Filed: 09.02.2001
IPC:
A61K 38/00 (2006.01) ,C07K 14/47 (2006.01) ,G01N 33/68 (2006.01)
Applicants: RIORDAN, John, R.[CA/US]; US (UsOnly)
CHANG, Xiu-bao[CA/US]; US (UsOnly)
MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH[US/US]; 200 First Street SW Rochester, MN 55905, US (AllExceptUS)
Inventors: RIORDAN, John, R.; US
CHANG, Xiu-bao; US
Agent: ELLINGER, Mark, S.; Fish & Richardson P.C., P.A. Suite 3300 60 South Sixth Street Minneapolis, MN 55402, US
Priority Data:
60/143,09009.07.1999US
60/146,09721.07.1999US
Title (EN) CFTR POLYPEPTIDES, FRAGMENTS THEREOF AND METHODS OF USE TO OVERCOME BIOSYNTHETIC MISPROCESSING
(FR) POLYPEPTIDES CFTR, LEURS FRAGMENTS ET LEURS PROCEDES D'UTILISATION POUR SURMONTER LES ERREURS DE TRAITEMENT DE BIOSYNTHESE
Abstract:
(EN) The invention relates to biosynthetic maturation of cell surface polypeptides and, more specifically, to particular CFTR polypeptides which exhibit increased transport to the cell surface and tripeptide amino acid sequences that promote or enhance transport of export-incompetent CFTR to the cell surface.
(FR) L'invention porte sur la maturation biosynthétique de polypeptides de la surface de cellules et plus spécifiquement sur les polypeptides particuliers CFTR qui se transportent plus facilement vers la surface des cellules et sur des séquences d'acides aminés tripeptidiques favorisant ou accroissant le transport vers la surface de cellules de CFTR incapables de s'exporter.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)