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1. (WO2001002566) METABOTROPIC GLUTAMATE RECEPTORS AND METHODS OF USE THEREFOR
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2001/002566    International Application No.:    PCT/US2000/017798
Publication Date: 11.01.2001 International Filing Date: 27.06.2000
IPC:
A61K 38/00 (2006.01), C07K 14/705 (2006.01)
Applicants: NEUROCRINE BIOSCIENCES, INC. [US/US]; 10555 Science Center Drive, San Diego, CA 92121 (US) (For All Designated States Except US).
SCHWARZ, David, A. [US/US]; (US) (For US Only).
MAKI, Richard, A. [US/US]; (US) (For US Only)
Inventors: SCHWARZ, David, A.; (US).
MAKI, Richard, A.; (US)
Agent: CHRISTIANSEN, William, T.; Seed Intellectual Property Law Group PLLC, Suite 6300, 701 Fifth Avenue, Seattle, WA 98104-7092 (US)
Priority Data:
09/346,326 02.07.1999 US
Title (EN) METABOTROPIC GLUTAMATE RECEPTORS AND METHODS OF USE THEREFOR
(FR) RECEPTEURS METABOTROPIQUES DU GLUTAMATE ET METHODES D'UTILISATION CORRESPONDANTES
Abstract: front page image
(EN)Compounds and methods for modulating glutamate binding are provided. Compounds include human metabotropic glutamate receptor polypeptides, and variants thereof that binds glutamate, or one or more agents that affects the ability of such a polypeptide to bind glutamate. The compounds may be used, for example, in the prevention and treatment of a variety of conditions associated with undesirable glutamate levels, including certain neurological disorders.
(FR)L'invention concerne des composés et des méthodes permettant de moduler la fixation du glutamate. Lesdits composés comprennent des polypeptides récepteurs métabotropiques du glutamate, et leurs variants qui fixent le glutamate, ou un ou plusieurs agents qui ont une incidence sur la capacité dudit polypeptide à fixer le glutamate. Ces composés peuvent être utilisés, par exemple, dans la prévention et le traitement de divers états pathologiques associés à des niveaux de glutamate indésirables, notamment certains troubles neurologiques.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)