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1. (WO2001002397) TRICYCLIC COMPOUNDS HAVING SPIRO UNION

Pub. No.:    WO/2001/002397    International Application No.:    PCT/JP2000/004374
Publication Date: Fri Jan 12 00:59:59 CET 2001 International Filing Date: Sat Jul 01 01:59:59 CEST 2000
IPC: C07D 498/20
Applicants: MOCHIDA PHARMACEUTICAL CO., LTD.

NISHIDA, Hidemitsu

SAITOH, Fumihiko

HARADA, Kousuke

SHIROMIZU, Ikuya

Inventors: NISHIDA, Hidemitsu

SAITOH, Fumihiko

HARADA, Kousuke

SHIROMIZU, Ikuya

Title: TRICYCLIC COMPOUNDS HAVING SPIRO UNION
Abstract:
Aromatic compounds having cyclic amino which are represented by general formula (I) or salts thereof. These compounds are useful as drugs, in particular, activated blood coagulation factor X inhibitors, exert a potent anticoagulation effect and can be orally administered. A pharmacophore derived from the above compounds which is useful in molecular designing Fxa inhibitors.