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1. (WO2001002387) N-IMIDAZOLYLMETHYL CARBOXAMIDES AS NITRIC OXIDE PRODUCTION INHIBITORS

Pub. No.:    WO/2001/002387    International Application No.:    PCT/JP2000/004302
Publication Date: Fri Jan 12 00:59:59 CET 2001 International Filing Date: Fri Jun 30 01:59:59 CEST 2000
IPC: C07D 233/54
C07D 401/06
C07D 401/14
C07D 405/12
C07D 405/14
Applicants: FUJISAWA PHARMACEUTICAL CO., LTD.
SHIMA, Ichiro
OHKAWA, Takehiko
OHNE, Kazuhiko
ZENKOH, Tatsuya
SATO, Kentaro
Inventors: SHIMA, Ichiro
OHKAWA, Takehiko
OHNE, Kazuhiko
ZENKOH, Tatsuya
SATO, Kentaro
Title: N-IMIDAZOLYLMETHYL CARBOXAMIDES AS NITRIC OXIDE PRODUCTION INHIBITORS
Abstract:
The present invention relates to a compound of formula (I) wherein each symbol is as defined in the specification, and pharmaceutically acceptable salts thereof. The compound (I) of the present invention and pharmaceutically acceptable salts thereof possess a strong inhibitory activity on the production of nitric oxide (NO), and are useful for prevention and/or treatment of NO-mediated diseases in human being and animals.