Search International and National Patent Collections

1. (WO2001002337) IMPROVEMENT TO THE EXCHANGE AND RELEASE OF AN AMINE FROM ITS CARBAMOYL FLUORIDE

Pub. No.:    WO/2001/002337    International Application No.:    PCT/FR2000/001911
Publication Date: Fri Jan 12 00:59:59 CET 2001 International Filing Date: Wed Jul 05 01:59:59 CEST 2000
IPC: C07C 209/74
C07C 211/52
Applicants: RHODIA CHIMIE
GUIDOT, Gilbert
ROCHIN, Christophe
SAINT-JALMES, Laurent
Inventors: GUIDOT, Gilbert
ROCHIN, Christophe
SAINT-JALMES, Laurent
Title: IMPROVEMENT TO THE EXCHANGE AND RELEASE OF AN AMINE FROM ITS CARBAMOYL FLUORIDE
Abstract:
The invention concerns a method for treating an aryl carbamoyl fluoride, comprising in its molecule at least a perhalogenated aliphatic carbon, which bears at least a halogen atom to be exchanged with the fluorine. The method comprises a step which consists in contacting said carbamoyl fluoride with hydrofluoric acid, the hydrofluoric acid/carbamoyl fluoride ratio being maintained during the reaction at a value less than 4, preferably 5. The invention is characterised in that said ratio is not more than 11. The invention is applicable to organic synthesis.