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1. (WO2001001890) STENT COATING

Pub. No.:    WO/2001/001890    International Application No.:    PCT/US2000/040105
Publication Date: Fri Jan 12 00:59:59 CET 2001 International Filing Date: Wed Jun 07 01:59:59 CEST 2000
IPC: A61F 2/06
A61K 9/00
A61L 31/10
A61L 31/16
Applicants: BOSTON SCIENTIFIC LIMITED
Inventors: YANG, Dachuan
STANSLASKI, Joel, L.
WANG, Lixiao
SMITH, Scott, R.
Title: STENT COATING
Abstract:
A stent having a polymeric coating for controllably releasing an included active agent. The polymeric coating inlcudes a blend of a first polymeric material, which if alone, would release the agent at a first, higher rate, and a second polymeric material, which if alone would release the agent at a second, lower rate over a longer time period. One stent coating utilizes a faster releasing hydrophilic polymeric material and a slower releasing hydrophobic material. One stent coating includes a blend of a faster releasing PLA-PEO copolymer and a slower releasing PLA-PCL copolymer. One active agent is Taxol. One use of the Taxol delivering stent is to inhibit restenosis following angioplasty.