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1. (WO2001000876) NANOPARTICLES HAVING OLIGONUCLEOTIDES ATTACHED THERETO AND USES THEREFOR
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2001/000876 International Application No.: PCT/US2000/017507
Publication Date: 04.01.2001 International Filing Date: 26.06.2000
Chapter 2 Demand Filed: 16.01.2001
IPC:
B82B 1/00 (2006.01) ,C07B 61/00 (2006.01) ,C07H 21/00 (2006.01) ,C12Q 1/68 (2006.01)
B PERFORMING OPERATIONS; TRANSPORTING
82
NANO-TECHNOLOGY
B
NANO-STRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS, MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES AS DISCRETE UNITS; MANUFACTURE OR TREATMENT THEREOF
1
Nano-structures formed by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
B
GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
61
Other general methods
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
H
SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
21
Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
68
involving nucleic acids
Applicants: MIRKIN, Chad, A.[US/US]; US
LETSINGER, Robert, L.[US/US]; US
MUCIC, Robert, C.[US/US]; US
STORHOFF, James, J.[US/US]; US
ELGHANIAN, Robert[US/US]; US
TATON, Thomas, Andrew[US/US]; US
Inventors: MIRKIN, Chad, A.; US
LETSINGER, Robert, L.; US
MUCIC, Robert, C.; US
STORHOFF, James, J.; US
ELGHANIAN, Robert; US
TATON, Thomas, Andrew; US
Agent: MIAO, Emily; McDonnell Boehnen Hulbert & Berghoff 300 South Wacker Drive Suite 3200 Chicago, IL 60606, US
Priority Data:
09/344,66725.06.1999US
60/200,16126.04.2000US
Title (EN) NANOPARTICLES HAVING OLIGONUCLEOTIDES ATTACHED THERETO AND USES THEREFOR
(FR) NANOPARTICULES AUXQUELLES SONT RATTACHES DES OLIGONUCLEOTIDES ET LEURS UTILISATIONS
Abstract:
(EN) The invention provides methods and kits for detecting nucleic acids. The methods employ particles and substrates having oligonucleotides attached to them. The presence of a nucleic acid produces a detectable change, such as a change in color, conductivity, or optical density. The invention further provides a method of synthesizing unique nanoparticle-oligonucleotide conjugates, the conjugates produced by the method, kits comprising the conjugates, nanomaterials and nanostructures comprising the conjugates, and methods of using the conjugates.
(FR) La présente invention concerne des procédés et des équipements de détection d'acides nucléiques. Ces procédés font intervenir des particules et des substrats auxquels sont rattachés des oligonucléotides. La présence d'un acide nucléique produit un changement détectable, tel qu'un changement de couleur, de conductivité ou de densité optique. Cette invention concerne également un procédé de synthèse de conjugués uniques nanoparticules-oligonucléotides, les conjugués obtenus par ce procédé, des équipements comprenant ces conjugués, des nanomatériaux et nanostructures comprenant ces conjugués, et des procédés d'utilisation de ces conjugués.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, UZ, VN, YU, ZA, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)