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1. (WO2001000646) ANTISENSE MODULATION OF JUN N-TERMINAL KINASE KINASE-2 EXPRESSION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2001/000646    International Application No.:    PCT/US2000/016242
Publication Date: 04.01.2001 International Filing Date: 13.06.2000
Chapter 2 Demand Filed:    12.01.2001    
IPC:
A61K 38/00 (2006.01), C12N 15/11 (2006.01)
Applicants: ISIS PHARMACEUTICALS, INC. [US/US]; 2292 Faraday Avenue, Carlsbad, CA 92008 (US) (For All Designated States Except US).
MONIA, Brett, P. [US/US]; (US) (For US Only).
COWSERT, Lex, M. [US/US]; (US) (For US Only)
Inventors: MONIA, Brett, P.; (US).
COWSERT, Lex, M.; (US)
Agent: LICATA, Jane, Massey; Law Offices of Jane Massey Licata, 66 E. Main Street, Marlton, NJ 08053 (US)
Priority Data:
09/344,001 24.06.1999 US
Title (EN) ANTISENSE MODULATION OF JUN N-TERMINAL KINASE KINASE-2 EXPRESSION
(FR) MODULATION ANTI-SENS DE L'EXPRESSION DE JUN N-TERMINAL KINASE KINASE-2
Abstract: front page image
(EN)Antisense compounds, compositions and methods are provided for modulating the expression of Jun N-terminal Kinase Kinase-2. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding Jun N-terminal Kinase Kinase-2. Methods of using these compounds for modulation of Jun N-terminal Kinase Kinase-2 expression and for treatment of diseases associated with expression of Jun N-terminal Kinase Kinase-2 are provided.
(FR)Cette invention se rapporte à des composés anti-sens, à des compositions et à des procédés servant à moduler l'expression de l'enzyme Jun N-terminal Kinase Kinase-2. Ces compositions comprennent des composés anti-sens, en particulier des oligonucléotides anti-sens, ciblés sur des acides nucléiques codant l'enzyme Jun N-terminal Kinase Kinase-2. Des procédés d'utilisation de ces composés pour moduler l'expression de cet enzyme et pour traiter des maladies associées à l'expression de cet enzyme sont également décrits.
Designated States: AE, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CR, CU, CZ, DE, DK, DM, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)