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1. (WO2001000646) ANTISENSE MODULATION OF JUN N-TERMINAL KINASE KINASE-2 EXPRESSION

Pub. No.:    WO/2001/000646    International Application No.:    PCT/US2000/016242
Publication Date: Fri Jan 05 00:59:59 CET 2001 International Filing Date: Wed Jun 14 01:59:59 CEST 2000
IPC: A61K 38/00
C12N 15/11
Applicants: ISIS PHARMACEUTICALS, INC.
MONIA, Brett, P.
COWSERT, Lex, M.
Inventors: MONIA, Brett, P.
COWSERT, Lex, M.
Title: ANTISENSE MODULATION OF JUN N-TERMINAL KINASE KINASE-2 EXPRESSION
Abstract:
Antisense compounds, compositions and methods are provided for modulating the expression of Jun N-terminal Kinase Kinase-2. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding Jun N-terminal Kinase Kinase-2. Methods of using these compounds for modulation of Jun N-terminal Kinase Kinase-2 expression and for treatment of diseases associated with expression of Jun N-terminal Kinase Kinase-2 are provided.