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Machine translation
1. (WO2001000587) AZOLYLBENZAMIDES AND ANALOGUES AND THEIR USE FOR TREATING OSTEOPOROSIS
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2001/000587 International Application No.: PCT/EP2000/005881
Publication Date: 04.01.2001 International Filing Date: 23.06.2000
Chapter 2 Demand Filed: 18.12.2000
IPC:
C07D 235/02 (2006.01) ,C07D 235/18 (2006.01) ,C07D 401/12 (2006.01) ,C07D 403/12 (2006.01) ,C07D 409/04 (2006.01) ,C07D 409/14 (2006.01) ,C07D 453/02 (2006.01) ,C07D 471/04 (2006.01) ,C07D 473/00 (2006.01)
Applicants: FARINA, Carlo[IT/IT]; IT (UsOnly)
GAGLIARDI, Stefania[IT/IT]; IT (UsOnly)
RAHMAN, Shahzad, Sharooq[GB/GB]; GB (UsOnly)
SMITHKLINE BEECHAM P.L.C.[GB/GB]; New Horizons Court Brentford Middlesex TW8 9EP, GB (AllExceptUS)
GLAXOSMITHKLINE S.P.A.[IT/IT]; Via Alessandro Fleming, 2 I-37135 Verona, IT (AllExceptUS)
Inventors: FARINA, Carlo; IT
GAGLIARDI, Stefania; IT
RAHMAN, Shahzad, Sharooq; GB
Agent: RUTTER, Keith ; SmithKline Beecham Two New Horizons Court Brentford, Middlesex, TW8 9EP, GB
Priority Data:
9914825.624.06.1999GB
Title (EN) AZOLYLBENZAMIDES AND ANALOGUES AND THEIR USE FOR TREATING OSTEOPOROSIS
(FR) AZOLYLBENZAMIDE ET ANALOGUES ET LEUR UTILISATION POUR TRAITER L'OSTEOPOROSE
Abstract: front page image
(EN) A compound of formula (I) or a salt thereof, or a solvate thereof, wherein: X represents oxygen, sulphur, or NRb; Y and Z each independently represent nitrogen, CH, CR1 or CR2; A represents an unsubstituted or substituted aryl group or an unsubstituted or substituted heterocyclyl group; Ra represents -C(O)NRsRt; R1 and R2 each independently represents hydrogen or specific substituents; and the use of such a compound in the treatment and/or prophylaxis of diseases associated with over activity of osteoclasts in mammals.
(FR) La présente invention concerne un composé de formule (I) ou un sel de celui-ci, ou un solvate de celui-ci, où: X représente oxygène, soufre, ou NRb; Y et Z représentent individuellement nitrogène, CH, CR1 ou Cr2; A représente un groupe aryle substitué ou non ou un groupe hétérocyclyle substitué ou non; Ra représente -C(O)NRsRt; R1 et R2 représentent individuellement hydrogène ou des substituants spécifiques; cette invention concernant également l'utilisation d'un tel composé dans le traitement et/ou la prophylaxie de maladies associées à la suractivité des ostéoclastes chez les mammifères.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)