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Machine translation
1. (WO2001000220) LIPOPROTEIN LIPASE (LPL) VARIANT THERAPEUTICS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2001/000220    International Application No.:    PCT/CA2000/000762
Publication Date: 04.01.2001 International Filing Date: 23.06.2000
Chapter 2 Demand Filed:    11.01.2001    
IPC:
A61K 38/46 (2006.01), A61K 48/00 (2006.01), C12N 9/20 (2006.01)
Applicants: THE UNIVERSITY OF BRITISH COLUMBIA [CA/CA]; University-Industry Liaison Office, IRC Building, Room 331, 2194 Health Sciences Mall, Vancouver, British Columbia V6T 1Z3 (CA) (For All Designated States Except US).
AMSTERDAM MOLECULAR THERAPEUTICS B.V. (AMT) [NL/NL]; Meibergdreef 61, NL-1105 BA Amsterdam (NL) (For All Designated States Except US).
ACADEMIC HOSPITAL AT THE UNIVERSITY OF AMSTERDAM [NL/NL]; Meibergdreef 9, NL-1105 AZ Amsterdam (NL) (For All Designated States Except US).
HAYDEN, Michael, R. [CA/CA]; (CA) (For US Only).
KASTELEIN, John, J., P. [NL/NL]; (NL) (For US Only)
Inventors: HAYDEN, Michael, R.; (CA).
KASTELEIN, John, J., P.; (NL)
Agent: KINGWELL, Brian, G.; Smart & Biggar Vancouver Centre, Suite 2200, Box 11560, 650 West Georgia Street, Vancouver, British Columbia V6B 4N8 (CA)
Priority Data:
99202048.7 24.06.1999 EP
Title (EN) LIPOPROTEIN LIPASE (LPL) VARIANT THERAPEUTICS
(FR) TRAITEMENT A BASE DE VARIANTS DE LPL
Abstract: front page image
(EN)The invention provides for the use of a therapeutic derived from a truncated lipoprotein lipase protein (LPL S447X), including nucleic acids encoding such proteins, for the treatment of conditions including LPL responsive conditions, such as cardiovascular disease, hypertension, LPL deficiency, high triglyceride levels, low HDL-cholesterol levels or atherosclerosis.
(FR)La présente invention concerne l'utilisation d'un traitement obtenu à partir d'une protéine lipoprotéine lipase tronquée (LPL S447X), ainsi que des acides nucléiques codant ces protéines, destiné au traitement des états tels que les états sensibles à la LPL, comme par exemple les maladies cardio-vasculaires, l'hypertension, les carences en LPL, des taux de triglycérides élevés, des taux de cholestérol HDL faibles ou l'athérosclérose.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)