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1. (WO2001000184) COMBINATION OF MTP INHIBITORS AND LIPID REDUCERS AND THE USE THEREOF IN MEDICAMENTS
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2001/000184 International Application No.: PCT/EP2000/005417
Publication Date: 04.01.2001 International Filing Date: 13.06.2000
Chapter 2 Demand Filed: 15.12.2000
IPC:
A61K 31/415 (2006.01) ,A61K 31/437 (2006.01) ,A61K 31/505 (2006.01) ,A61K 45/06 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
41
having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
415
1,2-Diazoles
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
4353
ortho- or peri-condensed with heterocyclic ring systems
437
the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
495
having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
505
Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45
Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
06
Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
Applicants:
GRÜTZMANN, Rudi [DE/DE]; DE (UsOnly)
MÜLLER, Ulrich [DE/DE]; DE (UsOnly)
BAYER AKTIENGESELLSCHAFT [DE/DE]; D-51368 Leverkusen, DE (AllExceptUS)
Inventors:
GRÜTZMANN, Rudi; DE
MÜLLER, Ulrich; DE
Common
Representative:
BAYER AKTIENGESELLSCHAFT; D-51368 Leverkusen, DE
Priority Data:
199 29 031.825.06.1999DE
Title (EN) COMBINATION OF MTP INHIBITORS AND LIPID REDUCERS AND THE USE THEREOF IN MEDICAMENTS
(FR) COMBINAISON D'INHIBITEURS DE PROTEINE DE TRANSFERT MICROSOMALE (MTP) ET D'AGENTS HYPOLIPIDEMIANTS ET LEUR UTILISATION DANS DES MEDICAMENTS
(DE) KOMBINATION VON MTP-INHIBITOREN UND LIPIDSENKERN UND IHRE VERWENDUNG IN ARZNEIMITTELN
Abstract:
(EN) The invention relates to the use of a combination consisting of at least one selected MTP inhibitor (constituent A) and of active substances, which influence the alteration of solids, as well as of vitamins (constituent B) for fighting cardiovascular diseases. The invention also relates to medicaments containing this combination and to the production thereof.
(FR) L'invention concerne l'utilisation d'une combinaison d'au moins un inhibiteur de MTP (constituant A) sélectionné et de principes actifs qui influent sur l'échange de solides, ainsi que de vitamines (constituant B), pour lutter contre des maladies cardio-vasculaires. L'invention concerne également des médicaments contenant cette combinaison et leur préparation.
(DE) Die Erfindung betrifft die Verwendung einer Kombination aus mindestens einem ausgewählten MTP-Inhibitor (Komponente A) und Wirkstoffen, die den Fettstoffwechsel beeinflussen sowie Vitamine (Komponente B) zur Bekämpfung von Herzkreislauferkrankungen, Arzneimittel enthaltend diese Kombination und ihre Herstellung.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG)
Publication Language: German (DE)
Filing Language: German (DE)