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Machine translation
1. (WO2001000138) USE OF HYDROXYDIPHENYL ETHER CLASS OF CHEMICALS, AS EXEMPLIFIED BY TRICLOSAN, AS AN ANTIMALARIAL AND IDENTIFICATION OF FATTY ACID SYNTHESIS AS ITS TARGET
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2001/000138 International Application No.: PCT/IN1999/000026
Publication Date: 04.01.2001 International Filing Date: 23.06.1999
IPC:
A61K 31/09 (2006.01) ,C12Q 1/16 (2006.01) ,C12Q 1/18 (2006.01)
Applicants: NAMITA, Surolia[IN/IN]; IN
JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH[IN/IN]; Jakkur Bangalore 560 064, IN (AllExceptUS)
Inventors: NAMITA, Surolia; IN
Agent: VAIDYANATHAN, Alamelu; 451, 2nd Cross 3rd Block, 3rd stage Basaveshwara Nagar Bangalore 560 079, IN
Priority Data:
Title (EN) USE OF HYDROXYDIPHENYL ETHER CLASS OF CHEMICALS, AS EXEMPLIFIED BY TRICLOSAN, AS AN ANTIMALARIAL AND IDENTIFICATION OF FATTY ACID SYNTHESIS AS ITS TARGET
(FR) UTILISATION D'UNE CLASSE DE PRODUITS CHIMIQUES HYDROXYDIPHENYL ETHER TELS QUE LE TRICLOSAN COMME AGENT ANTI-MALARIA, ET IDENTIFICATION DE LA SYNTHESE DES ACIDES GRAS COMME CIBLE DE CES PRODUITS CHIMIQUES
Abstract:
(EN) We report the use of hydroxydiphenyl ether class of chemicals, as exemplified by triclosan, (2,4,4'-trichloro-2'-hydroxydiphenyl ether), for both treatment and design of therapeutics for treatment of malaria. More specifically, the present invention relates to identification of fatty acid synthesis as target for this compound as well as a key enzyme involved in synthesizing them.
(FR) L'invention concerne l'utilisation d'une classe de produits chimiques hydroxydiphényl éther tels que le triclosan, et le (2,4,4'-trichloro-2'-hydroxydiphényl éther) pour à la fois traiter et concevoir des agents thérapeutiques permettant de traiter la malaria. L'invention concerne, plus spécifiquement, l'identification de la synthèse des acides gras comme cible de ce composé, et comme enzyme clé impliqué dans la synthèse desdits acides gras.
Designated States: AE, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZA, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, SD, SL, SZ, UG, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)