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1. (WO2000078992) MASS TRANSPORT LIMITED IN VIVO ANALYTE SENSOR
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2000/078992 International Application No.: PCT/US2000/016773
Publication Date: 28.12.2000 International Filing Date: 16.06.2000
Chapter 2 Demand Filed: 17.01.2001
IPC:
A61B 5/00 (2006.01) ,C12Q 1/00 (2006.01) ,G01N 27/49 (2006.01) ,G01N 33/487 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
27
Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means
26
by investigating electrochemical variables; by using electrolysis or electrophoresis
416
Systems
49
Systems involving the determination of the current at a single specific value, or small range of values, of applied voltage for producing selective measurement of one or more particular ionic species
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
483
Physical analysis of biological material
487
of liquid biological material
Applicants:
THERASENSE, INC. [US/US]; 1360 South Loop Road Alameda, CA 94502, US
Inventors:
SAY, James; US
TOMASCO, Michael, F.; US
SAKSLUND, Henning; US
AUDETT, Jay, D.; US
CHO, Hyun; US
YAMASAKI, Duane, O.; US
Agent:
HAMRE, Curtis, B.; Merchant & Gould P.C. P.O. Box 2903 Minneapolis, MN 55402-0903, US
Priority Data:
60/139,93618.06.1999US
60/194,61805.04.2000US
Title (EN) MASS TRANSPORT LIMITED IN VIVO ANALYTE SENSOR
(FR) CAPTEUR D'ANALYTE IN VIVO A TRANSFERT DE MASSE LIMITE
Abstract:
(EN) An in vivo electrochemical sensor including a working electrode, and an analyte-responsive sensing layer proximate the working electrode. The sensing layer is exposed at an edge of the sensor, wherein the sensor signal is limited, at least in part, by mass transport of analyte to the sensing layer. The sensor is configured and arranged for implantation into the body of a mammal for contact with body fluids of the mammal. The analyte diffuses to the sensing element via the edge of the sensor, thereby restricting mass transport of the analyte to the sensing element. This is because the solution-contacting surface area of the sensor edge is much smaller than an open face of the sensing layer.
(FR) L'invention concerne un capteur électrochimique in vivo comprenant une électrode de travail et une couche de détection sensible à l'analyte située à proximité de l'électrode de travail. La couche de détection est exposée à un bord du capteur, ce qui permet de limiter le signal de capteur, au moins partiellement, par transfert de masse de l'analyte en direction de la couche de détection. Le capteur est conçu pour être implanté dans le corps d'un mammifère et destiné à entrer en contact avec des fluides corporels du mammifère. L'analyte diffuse vers l'élément de détection par l'intermédiaire du bord du capteur, ce qui permet de restreindre le transfert de masse de l'analyte en direction de l'élément de détection. Ce phénomène est dû au fait que la surface du bord du capteur en contact avec la solution est beaucoup plus petite que celle d'une face ouverte de la couche de détection.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, UZ, VN, YU, ZA, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)