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1. (WO2000063441) SINGLE NUCLEOTIDE POLYMORPHISMS IN MITOCHONDRIAL GENES THAT SEGREGATE WITH ALZHEIMER'S DISEASE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2000/063441    International Application No.:    PCT/US2000/010906
Publication Date: 26.10.2000 International Filing Date: 19.04.2000
Chapter 2 Demand Filed:    02.11.2000    
IPC:
C12Q 1/68 (2006.01)
Applicants: MITOKOR [US/US]; 11494 Sorrento Valley Road, San Diego, CA 92121 (US) (For All Designated States Except US).
HERRNSTADT, Corinna [DE/US]; (US) (For US Only).
DAVIS, Robert, E. [US/US]; (US) (For US Only)
Inventors: HERRNSTADT, Corinna; (US).
DAVIS, Robert, E.; (US)
Agent: ROSENMAN, Stephen, J.; Seed Intellectual Property Law Group PLLC, Suite 6300, 701 Fifth Avenue, Seattle, WA 98104-7092 (US).
GOWSHALL, Jon, V.; Forrester & Boehmert, Franz-Joseph Strasse 38, D-80801 Munchen (DE)
Priority Data:
60/130,447 20.04.1999 US
60/160,901 22.10.1999 US
Title (EN) SINGLE NUCLEOTIDE POLYMORPHISMS IN MITOCHONDRIAL GENES THAT SEGREGATE WITH ALZHEIMER'S DISEASE
(FR) POLYMORPHISMES DE NUCLEOTIDES SIMPLES DANS DES GENES MITOCHONDRIAUX QUI SEGREGENT AVEC LA MALADIE D'ALZHEIMER
Abstract: front page image
(EN)Compositions and methods based on determination of single nucleotide polymorphisms in mtDNA or homoplasmic mtDNA mutations are provided that are useful for detecting the presence of or risk for having Alzheimer's disease (AD), and for identifying agents suitable for treating AD.
(FR)La présente invention porte sur des compositions et des méthodes fondées sur la détermination de polymorphismes de nucléotides simples dans l'ADN mt ou dans des mutations homoplasmiques d'ADN mt, utilisées pour détecter la présence de la maladie d'Alzheimer (AD) ou le risque de l'avoir, et pour identifier des agents appropriés pour traiter cette maladie.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)