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1. (WO2000063192) NOVEL POLYMORPHIC FORMS OF AN ANTIDIABETIC AGENT: PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2000/063192    International Application No.:    PCT/IB2000/000470
Publication Date: 26.10.2000 International Filing Date: 17.04.2000
Chapter 2 Demand Filed:    10.11.2000    
IPC:
A61K 31/538 (2006.01), C07D 265/38 (2006.01)
Applicants: DR. REDDY'S RESEARCH FOUNDATION [IN/IN]; 7-1-27, Ameerpet, Hyderabad 500 016 (IN) (For All Designated States Except US).
GADDAM, Om, Reddy [IN/IN]; (IN) (For US Only).
POTLAPALLY, Rajender, Kumar [IN/IN]; (IN) (For US Only).
SIRISILLA, Raju [IN/IN]; (IN) (For US Only).
KRISHNAMURTHI, Vyas [IN/IN]; (IN) (For US Only).
DHARMARAJA, Sreenivasa, Rao [IN/IN]; (IN) (For US Only).
MAMILLAPALLI, Ramabhadra, Sarma [IN/IN]; (IN) (For US Only)
Inventors: GADDAM, Om, Reddy; (IN).
POTLAPALLY, Rajender, Kumar; (IN).
SIRISILLA, Raju; (IN).
KRISHNAMURTHI, Vyas; (IN).
DHARMARAJA, Sreenivasa, Rao; (IN).
MAMILLAPALLI, Ramabhadra, Sarma; (IN)
Common
Representative:
DR. REDDY'S RESEARCH FOUNDATION; 7-1-27, Ameerpet, Hyderabad 500 016 (IN)
Priority Data:
PCT/IB99/00681 16.04.1999 IB
436/MAS/99 19.04.1999 IN
Title (EN) NOVEL POLYMORPHIC FORMS OF AN ANTIDIABETIC AGENT: PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
(FR) NOUVELLES FORMES POLYMORPHES D'UN AGENT ANTIDIABETIQUE, LEUR PROCEDE DE PREPARATION ET COMPOSITIONS PHARMACEUTIQUES LES RENFERMANT
Abstract: front page image
(EN)This invention relates to novel polymorphic/pseudopolymorphic forms of arginine salt of 3-[4-[2-(phenoxazin-10-yl)ethoxy]phenyl]-2-ethoxypropanoic acid, having formula (I). The invention also relates to a pharmaceutical composition comprising the novel polymorphic form or their mixture and a pharmaceutically acceptable carrier. The polymorphic forms of the present invention are more active, as antidiabetic and hypolipidemic agent, than the novel 3-[4-[2-(phenoxazin-10-yl)ethoxy]phenyl]-2-ethoxypropanoic acid.
(FR)L'invention concerne de nouvelles formes polymorphes/pseudompolymorphes d'un sel arginine d'acide 3-[4-[2-(phénoxazine-10-yl)éthoxy]phényl]-2-éthoxypropanoïque de formule (I). L'invention concerne aussi une composition pharmaceutique comprenant les nouvelles formes polymorphes ou leur mélange et un support pharmaceutiquement acceptable. Les formes polymorphes sont plus actives comme agent antidiabétique et hypolipidémique que le nouvel acide 3-[4-[2-(phénoxazin-10-yl)éthoxy]phényl]-2-éthoxypropanoïque.
Designated States: AE, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CR, CU, CZ, DE, DK, DM, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)