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Machine translation
1. (WO2000062735) TREATMENT OF NEOPLASMS WITH VIRUSES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2000/062735    International Application No.:    PCT/US2000/010204
Publication Date: 26.10.2000 International Filing Date: 17.04.2000
Chapter 2 Demand Filed:    13.11.2000    
IPC:
A61K 35/76 (2006.01), A61K 38/19 (2006.01), A61K 38/20 (2006.01), A61K 38/21 (2006.01), C07K 16/24 (2006.01), C12N 7/02 (2006.01), G01N 33/50 (2006.01)
Applicants: PRO-VIRUS, INC. [US/US]; 16020 Industrial Drive, Gaithersburg, MD 20877 (US) (For All Designated States Except US).
ROBERTS, Michael, S. [US/US]; (US) (For US Only).
LORENCE, Robert, M. [US/US]; (US) (For US Only).
GROENE, William, S. [US/US]; (US) (For US Only).
RABIN, Harvey [US/US]; (US) (For US Only).
VON BORSTEL, Reid, W. [US/US]; (US) (For US Only)
Inventors: ROBERTS, Michael, S.; (US).
LORENCE, Robert, M.; (US).
GROENE, William, S.; (US).
RABIN, Harvey; (US).
VON BORSTEL, Reid, W.; (US)
Agent: BYRNE, Thomas, E.; Nixon & Vanderhye P.C., Suite 800, 1100 North Glebe Road, Arlington, VA 22201-4714 (US)
Priority Data:
09/292,376 15.04.1999 US
Title (EN) TREATMENT OF NEOPLASMS WITH VIRUSES
(FR) TRAITEMENT DE NEOPLASMES AVEC DES VIRUS
Abstract: front page image
(EN)The subject invention relates to viruses that are able to replicate and thereby kill neoplastic cells with a deficiency in the IFN-mediated antiviral response, and their use in treating neoplastic disease including cancer and large tumors. RNA and DNA viruses are useful in this regard. The invention also relates to methods for the selection, design, purification and use of such viruses for cancer therapy.
(FR)L'invention concerne des virus qui sont capables de se répliquer et donc de tuer des cellules néoplastiques présentant une déficience de la réponse antivirale médiée par interférons, et leur utilisation dans le traitement de maladies néoplastiques, dont le cancer et les grosses tumeurs. Selon cet aspect, les virus d'ARN et d'ADN sont utiles. Cette invention concerne également des méthodes de sélection, de conception, de purification et d'utilisation de ces virus en thérapie du cancer.
Designated States: AE, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CR, CU, CZ, DE, DK, DM, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)