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Pub. No.:    WO/2000/061129    International Application No.:    PCT/US2000/009374
Publication Date: 19.10.2000 International Filing Date: 07.04.2000
Chapter 2 Demand Filed:    08.11.2000    
A61K 31/496 (2006.01), C07D 249/12 (2006.01)
Applicants: SEPRACOR INC. [US/US]; 111 Locke Drive, Marlborough, MA 01752 (US) (For All Designated States Except US).
BARBERICH, Timothy, J. [US/US]; (US) (For US Only).
RUBIN, Paul, D. [US/US]; (US) (For US Only).
YELLE, William, E. [US/US]; (US) (For US Only)
Inventors: BARBERICH, Timothy, J.; (US).
RUBIN, Paul, D.; (US).
YELLE, William, E.; (US)
Agent: GIOENI, Mary, Louise; Heslin & Rothenberg, P.C., 5 Columbia Circle, Albany, NY 12203 (US)
Priority Data:
60/128,481 09.04.1999 US
Abstract: front page image
(EN)The S-isomer of the hydroxy metabolite of nefazodone, S-hydroxynefazodone, is an effective treatment for depression which does not give rise to the adverse effects associated with nefazodone. S-hydroxynefazodone is also useful in the treatment of migraine headaches, panic disorders, post traumatic stress disorder and sleep disorders.
(FR)L'invention concerne l'isomère-s du métabolite hydroxy de la néfazodone, ou S-hydroxynéfazodone, lequel constitue un traitement efficace contre la dépression ne provoquant pas les effets secondaires associés à la néfazodone. La S-hydroxynéfazodone est également utile pour le traitement des migraines, des attaques de panique, des états de stress post-traumatique et des troubles du sommeil.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)