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Machine translation
1. (WO2000060945) SOLUBLE RECOMBINANT ENDOSTATIN AND METHOD OF MAKING SAME FROM $i(STREPTOMYCES SP)
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2000/060945    International Application No.:    PCT/US2000/009747
Publication Date: 19.10.2000 International Filing Date: 12.04.2000
Chapter 2 Demand Filed:    13.11.2000    
IPC:
A61K 38/39 (2006.01), C07K 14/78 (2006.01), C12N 15/76 (2006.01)
Applicants: MERCK & CO., INC. [US/US]; 126 East Lincoln Avenue, Rahway, NJ 07065-0907 (US) (For All Designated States Except US).
DESANTI, Charles, L. [US/US]; (US) (For US Only).
STROHL, William, R. [US/US]; (US) (For US Only)
Inventors: DESANTI, Charles, L.; (US).
STROHL, William, R.; (US)
Common
Representative:
MERCK & CO., INC.; 126 East Lincoln Avenue, Rahway, NJ 07065-0907 (US)
Priority Data:
60/129,084 13.04.1999 US
Title (EN) SOLUBLE RECOMBINANT ENDOSTATIN AND METHOD OF MAKING SAME FROM $i(STREPTOMYCES SP)
(FR) ENDOSTATINE RECOMBINEE, SOLUBLE, ET PROCEDE DE PREPARATION A PARTIR DE $i(STREPTOMYCES SP)
Abstract: front page image
(EN)A method of making soluble recombinant endostatin in $i(Streptomyces) is disclosed. Preparations containing the soluble recombinant endostatin are provided for the inhibition of angiogenesis or the treatment of cancer. Assays using the soluble recombinant endostatin are also provided.
(FR)L'invention concerne un procédé de préparation d'une endostatine recombinée, soluble, dans $i(Streptomyces). Elle concerne également des préparations contenant cette endostatine recombinée, soluble, destinée à inhiber l'angiogenèse ou destinée au traitement du cancer. L'invention concerne également des dosages dans lesquels on utilise cette endostatine recombinée, soluble.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)