WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2000060072) POLYNUCLEOTIDE SYNTHESIS USING A PROCESSING ENZYME
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2000/060072    International Application No.:    PCT/GB2000/001289
Publication Date: 12.10.2000 International Filing Date: 06.04.2000
Chapter 2 Demand Filed:    26.10.2000    
IPC:
C07K 14/215 (2006.01), C12N 9/12 (2006.01), C12N 13/00 (2006.01), C12P 19/34 (2006.01)
Applicants: MEDICAL BIOSYSTEMS LTD. [GB/GB]; The Old Mill, Beaston Cross, Broadhempston, Nr. Totnes, Devon TQ9 6BX (GB) (For All Designated States Except US).
DENSHAM, Daniel, Henry [GB/GB]; (GB) (For US Only)
Inventors: DENSHAM, Daniel, Henry; (GB)
Agent: GILL JENNINGS & EVERY; Broadgate House, 7 Eldon Street, London EC2M 7LH (GB)
Priority Data:
9907813.1 06.04.1999 GB
Title (EN) POLYNUCLEOTIDE SYNTHESIS USING A PROCESSING ENZYME
(FR) SYNTHESE DE POLYNUCLEOTIDES AU MOYEN D'UNE ENZYME DE MATURATION
Abstract: front page image
(EN)A method for polynucleotide synthesis, comprises the steps of: (i) reacting a polynucleotide processive enzyme, e.g. a polymerase or TdT, with a nucleotide substrate under conditions suitable for enzyme activity; and (ii) modulating the conformation of the enzyme, e.g. using radiation, to allow incorporation of a predetermined nucleotide.
(FR)L'invention concerne un procédé pour la synthèse de polynucléotides, consistant : (i) à faire réagir une enzyme de maturation polynucléotidique telle qu'une polymérase ou une transférase-terminale (TdT), avec un substrat nucléotidique aux conditions convenant à l'activité enzymatique; et (ii) à moduler la conformation d'une enzyme, au moyen notamment de radiations, pour permettre l'incorporation d'un nucléotide prédéterminé.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)