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Machine translation
1. (WO2000059900) P38?MAPK¿ INHIBITOR AND USES THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2000/059900    International Application No.:    PCT/US2000/008775
Publication Date: 12.10.2000 International Filing Date: 31.03.2000
Chapter 2 Demand Filed:    30.10.2000    
IPC:
A61K 31/4439 (2006.01)
Applicants: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS [US/US]; 2404 North University Avenue, Little Rock, AR 72207-3608 (US)
Inventors: MEHTA, Kamal, D.; (US).
SINGH, Rajesh, P.; (IN)
Agent: ADLER, Benjamin, A.; McGregor & Adler, 8011 Candle Lane, Houston, TX 77071 (US)
Priority Data:
60/127,343 01.04.1999 US
Title (EN) P38?MAPK¿ INHIBITOR AND USES THEREOF
(FR) INHIBITEUR DE P38?MAPK¿ ET SES UTILISATIONS
Abstract: front page image
(EN)The present invention demonstrates that p38?MAPK¿ inhibitor induces low density lipoprotein receptor expression 6-8 fold, and further provides the application of such inhibitor in the treatment of hypercholesterolemia.
(FR)Selon l'invention, l'inhibiteur de p38?MAPK¿ induit par 6-8 fois l'expression du récepteur de la lipoprotéine de faible densité et autorise l'application d'un tel inhibiteur dans le traitement de l'hypercholestérolémie.
Designated States: AU, CA, JP, MX.
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE).
Publication Language: English (EN)
Filing Language: English (EN)