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Machine translation
1. (WO2000058466) PROTEASE RESISTANT FLINT ANALOGS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2000/058466    International Application No.:    PCT/US2000/006418
Publication Date: 05.10.2000 International Filing Date: 20.03.2000
Chapter 2 Demand Filed:    10.10.2000    
IPC:
A61K 38/00 (2006.01), C07K 14/705 (2006.01)
Applicants: ELI LILLY AND COMPANY [US/US]; Lilly Corporate Center, Indianapolis, IN 46285 (US) (For All Designated States Except US).
MICANOVIC, Radmila [US/US]; (US) (For US Only).
RATHNACHALAM, Radhakrishnan [IN/US]; (US) (For US Only).
WITCHER, Derrick, Ryan [US/US]; (US) (For US Only)
Inventors: MICANOVIC, Radmila; (US).
RATHNACHALAM, Radhakrishnan; (US).
WITCHER, Derrick, Ryan; (US)
Agent: WEBSTER, Thomas, D.; Eli Lilly and Company, Lilly Corporate Center, Indianapolis, IN 46285 (US)
Priority Data:
60/126,839 30.03.1999 US
60/140,073 21.06.1999 US
60/147,071 04.08.1999 US
60/160,524 20.10.1999 US
60/160,669 21.10.1999 US
60/172,744 20.12.1999 US
60/178,184 26.01.2000 US
Title (EN) PROTEASE RESISTANT FLINT ANALOGS
(FR) ANALOGUES DE FLINT RESISTANT AUX PROTEASES
Abstract: front page image
(EN)The invention relates to FLINT analogs that are resistant to proteolysis $i(in vivo) and $i(in vitro) at amino acid position 218 of mature FLINT, clinical and therapeutic uses thereof, and pharmaceutical formulations comprising said analogs.
(FR)L'invention concerne des analogues de FLINT (FAS Ligand Inhibitory proteins /protéines inhibitrices de ligands FAS), qui résistent à la protéolyse $i(in vivo) et $i(in vitro) au niveau de la position 218 de l'aminoacide du FLINT mature, des utilisations cliniques et thérapeutiques desdits analogues et des formules pharmaceutiques comprenant lesdits analogues.
Designated States: AE, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)