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Machine translation
1. (WO2000058363) MONOCLONAL ANTIBODIES, ANTIGENS AND DIAGNOSIS AND THERAPY OF MALIGNANT DISEASES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2000/058363    International Application No.:    PCT/IL1999/000518
Publication Date: 05.10.2000 International Filing Date: 30.09.1999
Chapter 2 Demand Filed:    29.10.2000    
IPC:
A61K 38/00 (2006.01), C07K 7/06 (2006.01), C07K 7/08 (2006.01), C07K 16/28 (2006.01), G01N 33/569 (2006.01), G01N 33/574 (2006.01)
Applicants: MOR- RESEARCH APPLICATIONS LTD. [IL/IL]; 23 Hasivim Street Kiriat Matalon P.O. Box 7590 49170 Petach Tikva (IL) (For All Designated States Except US).
HARDY, Britta [IL/IL]; (IL) (For US Only).
NOVOGRODSKY, Abraham [IL/IL]; (IL) (For US Only)
Inventors: HARDY, Britta; (IL).
NOVOGRODSKY, Abraham; (IL)
Agent: REINHOLD COHN AND PARTNERS; P.O. Box 4060 61040 Tel-Aviv (IL)
Priority Data:
129299 31.03.1999 IL
Title (EN) MONOCLONAL ANTIBODIES, ANTIGENS AND DIAGNOSIS AND THERAPY OF MALIGNANT DISEASES
(FR) ANTICORPS MONOCLONAUX, ANTIGENES ET DIAGNOSTIC ET TRAITEMENT D'AFFECTIONS MALIGNES
Abstract: front page image
(EN)The invention concerns novel DNA and amino acid sequences of monoclonal antibodies (mAbs) raised against lymphoblastoid cells and peptides to which the mAbs bind to. The invention also concerns diagnostic assays using said antibodies or peptides for detecting individuals with a high probability of having a malignant disease and, at times, for detecting an individual having a specific malignant disease. The invention further concerns pharmaceutical compositions comprising the mAbs or peptides of the invention for use in the treatment of various malignant diseases as well as methods for the treatment of malignant diseases using the mAbs or peptides of the invention.
(FR)L'invention concerne un nouvel ADN et des séquence d'acides aminés d'anticorps monoclonaux (mAbs) agissant contre des cellules et des peptides lymphoblastoïdes auxquels les anticorps monoclonaux se lient. L'invention concerne également des dosages de diagnostic faisant intervenir ces anticorps ou ces peptides pour détecter chez des individus une forte probabilité de souffrir d'une affection maligne et, parfois, pour détecter chez un individu une affection maligne spécifique. L'invention concerne en outre des compositions pharmaceutiques comprenant les anticorps monoclonaux ou les peptides selon l'invention destinés à s'utiliser dans le traitement de nombreuses affections malignes, ainsi que des méthodes de traitement d'affections malignes grâce aux anticorps monoclonaux ou peptides selon l'invention.
Designated States: AE, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CR, CU, CZ, DE, DK, DM, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)