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Machine translation
1. (WO2000058359) RETRO-INVERSO PROSAPOSIN-DERIVED PEPTIDES AND USE THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2000/058359    International Application No.:    PCT/US2000/008550
Publication Date: 05.10.2000 International Filing Date: 29.03.2000
Chapter 2 Demand Filed:    24.10.2000    
IPC:
A61K 38/00 (2006.01), C07K 14/475 (2006.01)
Applicants: MYELOS CORPORATION [US/US]; Suite M, 4940 Carroll Canyon Road, San Diego, CA 92121 (US) (For All Designated States Except US).
O'BRIEN, John, S. [US/US]; (US) (For US Only).
WRIGHT, David, E. [US/US]; (US) (For US Only)
Inventors: O'BRIEN, John, S.; (US).
WRIGHT, David, E.; (US)
Agent: HUNT, Dale, C.; 16th Floor, 620 Newport Center Drive, Newport Beach, CA 92660 (US)
Priority Data:
60/126,991 30.03.1999 US
Title (EN) RETRO-INVERSO PROSAPOSIN-DERIVED PEPTIDES AND USE THEREOF
(FR) PEPTIDES RETRO-INVERSO DERIVES DE LA PROSAPOSINE ET LEUR UTILISATION
Abstract: front page image
(EN)Retro-inverso peptide analogs derived from the active neurotrophic region of saposin C which include the amino acid sequence LLEENNDL (all D-amino acids). These peptides induce neurite outgrowth $i(in vitro), prevent programmed cell death, induce myelination and have an analgesic effect. They are useful in the treatment of central and peripheral nervous system disorders and neuropathic pain.
(FR)La présente invention concerne des analogues peptidiques rétro-inverso dérivés de la région neurotrophique active de la saposine C qui comprend la séquence d'acides aminés LLEENNDL (tous des acides aminés D). Lesdits peptides provoquent la formation de névrite $i(in vitro), inhibent l'apoptose, stimulent la myélinisation et possèdent un effet analgésique. Ils sont également utiles dans le traitement de troubles du système nerveux central et périphérique et de la douleur névropathique.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)