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1. (WO2000058351) ZWITTERMICIN A BIOSYNTHETIC GENE FROM $i(BACILLUS CEREUS)
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2000/058351    International Application No.:    PCT/US2000/007570
Publication Date: 05.10.2000 International Filing Date: 22.03.2000
Chapter 2 Demand Filed:    13.10.2000    
IPC:
C12N 9/00 (2006.01), C12N 9/02 (2006.01), C12N 9/10 (2006.01), C12N 15/82 (2006.01)
Applicants: WISCONSIN ALUMNI RESEARCH FOUNDATION [US/US]; 614 Walnut Street, Madison, WI 53707-7365 (US)
Inventors: HANDELSMAN, Jo; (US).
MILNER, Jocelyn, L.; (US).
STOHL, Elizabeth, A.; (US).
EMMERT, Elizabeth, A.; (US)
Agent: LEONE, Joseph, T.; DeWitt Ross & Stevens S.C., 8000 Excelsior Drive, Suite 401, Madison, WI 53717-1914 (US)
Priority Data:
60/125,769 23.03.1999 US
Title (EN) ZWITTERMICIN A BIOSYNTHETIC GENE FROM $i(BACILLUS CEREUS)
(FR) GENES DE ZWITTERMICINE A A PARTIR DE BACILLUS CEREUS
Abstract: front page image
(EN)Disclosed herein is an isolated DNA construct encoding enzymes necessary for the biological synthesis of zwittermicin A, a unique aminopolyol antibiotic produced by $i(Bacillus cereus) that is active against diverse bacteria and lower eucaryotes. Also disclosed herein are hosts transformed to contain and express the DNA construct, and a method to produce zwittermicin A using the construct and transformed hosts.
(FR)La présente invention concerne une construction d'ADN isolée codant les enzymes nécessaires à la biosynthèse de la zwittermicine A, un antibiotique d'aminopolyol unique produit par le $i(Bacillus cereus) présentant une activité vis-à-vis de diverses bactéries et des eucaryotes inférieurs. L'invention concerne également des hôtes transformés pour contenir et exprimer la construction d'ADN, et un procédé de production de zwittermicine A mettant en oeuvre ladite construction et les hôtes transformés.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)