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1. (WO2000058283) BIOCATALYST AND ITS USE IN ENZYMATIC RESOLUTION OF RACEMIC BETA-LACTAMS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2000/058283    International Application No.:    PCT/GB2000/001198
Publication Date: 05.10.2000 International Filing Date: 29.03.2000
Chapter 2 Demand Filed:    25.08.2000    
IPC:
C07D 205/12 (2006.01), C12N 9/86 (2006.01)
Applicants: CHIROTECH TECHNOLOGY LIMITED [GB/GB]; Cambridge Science Park, Milton Road, Cambridge CB4 0WG (GB) (For All Designated States Except US).
TAYLOR, Stephen, John, Clifford [GB/GB]; (GB) (For US Only).
KEENE, Philip, Alexander [GB/GB]; (GB) (For US Only)
Inventors: TAYLOR, Stephen, John, Clifford; (GB).
KEENE, Philip, Alexander; (GB)
Agent: GILL JENNINGS & EVERY; Broadgate House, 7 Eldon Street, London EC2M 7LH (GB)
Priority Data:
9907415.5 31.03.1999 GB
Title (EN) BIOCATALYST AND ITS USE IN ENZYMATIC RESOLUTION OF RACEMIC BETA-LACTAMS
(FR) BIOCATALYSEUR ET SON UTILISATION DANS LA RÉSOLUTION ENZYMATIQUE DE BÉTA-LACTAME RACÉMIQUE
Abstract: front page image
(EN)A process for the preparation of an enantiomerically enriched $g(b)-lactam, comprises enantioselective hydrolysis of the corresponding racemic $g(b)-lactam in the presence of a lactamase enzyme capable of enantioselective hydrolysis of 3-azatricyclo[4.2.1.0?2,5¿]non-7-en-4-one and 7-azabicyclo[4.2.0]oct-4-en-8-one.
(FR)Procédé de préparation d'un $g(b)-lactame enrichi énantiomèriquement, caractérisé en ce qu'il comprend l'hydrolyse énantiosélective du $g(b)-lactame correspondant en présence d'une lactamase capable d'effectuer l'hydrolyse énantiosélective de 3-azatricyclo[4.2.1.0?2,5¿]non-7-èn-4-one et de 7-azabicyclo[4.2.0]oct-4-èn-8-one.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)