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1. (WO2000058264) METHOD FOR THE SYNTHESIS OF NON-SYMMETRICAL DTPA COMPOUNDS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2000/058264    International Application No.:    PCT/US2000/007461
Publication Date: 05.10.2000 International Filing Date: 21.03.2000
Chapter 2 Demand Filed:    25.10.2000    
IPC:
C07C 227/08 (2006.01), C07C 227/18 (2006.01), C07C 229/16 (2006.01)
Applicants: MALLINCKRODT INC. [US/US]; 675 McDonnell Boulevard, P.O. Box 5840, St. Louis, MO 63134 (US) (For All Designated States Except US).
ACHILEFU, Samuel, I. [NG/US]; (US) (For US Only).
SRINIVASAN, Ananthachari [US/US]; (US) (For US Only)
Inventors: ACHILEFU, Samuel, I.; (US).
SRINIVASAN, Ananthachari; (US)
Agent: BOONE, Jeffrey, S.; 675 McDonnell Boulevard, P.O. Box 5840, St. Louis, MO 63134 (US)
Priority Data:
60/126,482 26.03.1999 US
Title (EN) METHOD FOR THE SYNTHESIS OF NON-SYMMETRICAL DTPA COMPOUNDS
(FR) PROCEDE DE SYNTHESE DE COMPOSES D'ACIDE DIETHYLENE TRIAMINEPENTA ACETIQUE NON SYMETRIQUES
Abstract: front page image
(EN)The synthesis of compounds of formula (XIV) wherein each R¿4? is an alkyl group having 1 to 15 carbon atoms, and R¿6? is a linking moiety having 1 to 10 carbon atoms, is disclosed. These compounds are useful intermediates in the synthesis of compounds of formula (X). These compounds are useful in the preparation of nuclear pharmaceuticals such as those used for tumor imaging or tumor therapy.
(FR)L'invention concerne la synthèse de composés de formule (XIV) dans laquelle R¿4? représente un groupe alkyle possédant 1 à 15 atomes de carbone et R¿6? représente un fragment de liaison possédant 1 à 10 atomes de carbone. Ces composés sont des intermédiaires utiles dans la synthèse de composés de formule (X). Lesdits composés sont utiles dans la préparation de produits pharmaceutiques nucléaires, tels que ceux utilisés pour l'imagerie ou le traitement de tumeurs.
Designated States: AE, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CR, CU, CZ, DE, DK, DM, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)