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1. (WO2000057886) DISPERSIBLE MACROLIDE COMPOUNDS AND METHOD FOR THE PRODUCTION THEREOF

Pub. No.:    WO/2000/057886    International Application No.:    PCT/FR2000/000800
Publication Date: Oct 5, 2000 International Filing Date: Mar 30, 2000
IPC: A61K 9/00
Applicants: CLL PHARMA
ZAKARIAN, Noël
GIMET, René
LARUELLE, Claude
TOSELLI, Dominique
Inventors: ZAKARIAN, Noël
GIMET, René
LARUELLE, Claude
TOSELLI, Dominique
Title: DISPERSIBLE MACROLIDE COMPOUNDS AND METHOD FOR THE PRODUCTION THEREOF
Abstract:
The invention relates to dispersible tablets containing macrolides as active ingredients either on their own or associated with other active ingredients, in addition to a method for the production thereof. The dispersible tablets are characterized in that the macrolide is chosen from a group that is made up of pristinamycin, azithromycin, roxithromycin, clarithromycin and spiramycin, and is present in a basic form in proportions ranging from 20-60 % of the total weight of said tablets. The dispersible tablets are also characterized in that they contain at least one disintegrator in proportions ranging from 1-25 % of the total weight of said tablets in addition to at least one sweetening agent. Application: antibiotherapy.