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Machine translation
1. (WO2000057837) COMPOSITIONS AND METHODS FOR EFFECTING THE LEVELS OF CHOLESTEROL
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2000/057837    International Application No.:    PCT/US2000/007870
Publication Date: 05.10.2000 International Filing Date: 24.03.2000
Chapter 2 Demand Filed:    23.10.2000    
IPC:
A61K 38/00 (2006.01), A61K 48/00 (2006.01), C07K 16/40 (2006.01), C12N 9/20 (2006.01)
Applicants: AVENTIS PHARMACEUTICALS PRODUCTS INC. [US/US]; Route 202-206, P.O. Box 6800, Bridgewater, NJ 08807 (US) (For All Designated States Except US).
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA [US/US]; University of Pennsylvania, Suite 300, Office of Research Administration, 133 South 36th Street, Philadelphia, PA 19104-3246 (US) (For All Designated States Except US).
JAYE, Michael [US/US]; (US) (For US Only).
LYNCH, Kevin, J. [US/US]; (US) (For US Only).
AMIN, Dilip, V. [US/US]; (US) (For US Only).
DOAN, Kim-Anh, Thi [US/US]; (US) (For US Only).
MARCHADIER, Dawn [CA/US]; (US) (For US Only).
MAUGEAIS, Cyrille [FR/US]; (US) (For US Only).
RADER, Daniel, J. [US/US]; (US) (For US Only).
KRAWIEC, John, A. [US/US]; (US) (For US Only).
SOUTH, Victoria, J. [US/US]; (US) (For US Only)
Inventors: JAYE, Michael; (US).
LYNCH, Kevin, J.; (US).
AMIN, Dilip, V.; (US).
DOAN, Kim-Anh, Thi; (US).
MARCHADIER, Dawn; (US).
MAUGEAIS, Cyrille; (US).
RADER, Daniel, J.; (US).
KRAWIEC, John, A.; (US).
SOUTH, Victoria, J.; (US)
Agent: BARRON, Alexis; Synnestvedt & Lechner LLP, 2600 Aramark Tower, 1101 Market Street, Philadelphia, PA 19107-2950 (US)
Priority Data:
09/277,401 26.03.1999 US
Title (EN) COMPOSITIONS AND METHODS FOR EFFECTING THE LEVELS OF CHOLESTEROL
(FR) COMPOSITIONS ET PROCEDES AGISSANT SUR LES TAUX DE CHOLESTEROL DES LIPOPROTEINES DE HAUTE DENSITE (HDL) ET DES APOLIPOPROTEINES AI, SUR LES TAUX DE CHOLESTEROL DES LIPOPROTEINES DE TRES FAIBLE DENSITE (VLDL) ET SUR LE TAUX DE CHOLESTEROL DES LIPOPROTEINES DE FAIBLE DENSITE (LDL)
Abstract: front page image
(EN)Compositions and methods for raising the level of HDL cholesterol and apolipoprotein AI in a patient and for lowering the levels of VLDL cholesterol and LDL cholesterol in a patient, including compositions and methods which effect the expression of a gene, LIPG, which encodes a lipase enzyme that is a member of the tryacylglycerol lipase family or which effect the enzymatic activity of the enzyme.
(FR)La présente invention concerne des compositions et des procédés permettant d'élever le taux de cholestérol des HDL et des apolipoprotéines AI chez un patient et de réduire le taux de cholestérol des VLDL et des LDL chez un patient. Ces compositions et ces procédés agissent sur l'expression d'un gène, LIPG, qui code une lipase qui fait partie de la famille des triacylglycériol lipases ou qui agit sur l'activité enzymatique de cette enzyme.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)