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1. WO2000043786 - TESTING DEVICE AND METHOD CHROMATOGRAPHIC

Publication Number WO/2000/043786
Publication Date 27.07.2000
International Application No. PCT/FR2000/000141
International Filing Date 21.01.2000
IPC
G01N 33/543 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
543with an insoluble carrier for immobilising immunochemicals
G01N 33/558 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
558using diffusion or migration of antigen or antibody
CPC
G01N 33/54386
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
543with an insoluble carrier for immobilising immunochemicals
54366Apparatus specially adapted for solid-phase testing
54386Analytical elements
G01N 33/558
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
558using diffusion or migration of antigen or antibody
Applicants
  • ADIATEC [FR/FR]; 1, Place Alexis Ricordeau Cedex 1 F-44093 Nantes, FR (AllExceptUS)
  • LESSER, Joël [FR/FR]; FR (UsOnly)
Inventors
  • LESSER, Joël; FR
Priority Data
99/0065021.01.1999FR
Publication Language French (FR)
Filing Language French (FR)
Designated States
Title
(EN) TESTING DEVICE AND METHOD CHROMATOGRAPHIC
(FR) DISPOSITIF DE TEST ET PROCEDE IMMUNOCHROMATOGRAPHIQUES
Abstract
(EN)
The invention concerns a method for producing a testing device and a method for quantifying results obtained by chromatographic immunoassay processes enabling to display values or domains of values to colouring or signal colouring intensity levels, and by comparing the colouring or the colouring intensity with that of an internal calibrating control. The invention also concerns a method for defining colouring intensity or a reference colouring and for adjusting the colouring intensity of the internal calibrating control signal. The method further concerns a method for interpreting results enabling to establish correspondences between the result and one or several value ranges of the searched element. Said device is useful, for example but not exclusively, for distinguishing different proportions of antibodies in a biological sample. The invention is also useful in kits for analysis.
(FR)
L'invention concerne un procédé de réalisation d'un dispositif de test et un procédé pour la quantification de résultats obtenus par des méthodes immunochromatographiques permettant d'affecter des valeurs ou domaines de valeurs à des colorations ou des intensités de coloration de signal, et par comparaison de la coloration ou de l'intensité de coloration du résultat avec celle d'un témoin interne de calibrage. Une procédure pour définir une intensité de coloration ou une coloration de référence est décrite ainsi que pour ajuster l'intensité de coloration du signal du témoin interne de calibrage. Une procédure d'interprétation des résultats permettant l'établissement de correspondances entre le résultat et une ou des plages de valeurs de l'élément recherché est également décrite. Ce dispositif est applicable par exemple et de façon non limitative à la distinction de différents taux d'anticorps spécifiques dans un échantillon biologique. Son utilisation dans des trousses d'analyse est inclue.
Also published as
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