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1. WO2000043775 - METHOD OF CHARACTERIZATION OF BIOLOGICAL ENTITIES

Publication Number WO/2000/043775
Publication Date 27.07.2000
International Application No. PCT/US2000/001550
International Filing Date 22.01.2000
Chapter 2 Demand Filed 22.08.2000
IPC
G01N 15/14 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
15Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
10Investigating individual particles
14Electro-optical investigation
G01N 21/35 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
17Systems in which incident light is modified in accordance with the properties of the material investigated
25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
31Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
35using infra-red light
G01N 21/64 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
63optically excited
64Fluorescence; Phosphorescence
CPC
G01N 15/1463
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
15Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
10Investigating individual particles
14Electro-optical investigation, e.g. flow cytometers
1456without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
1463using image analysis for extracting features of the particle
G01N 2015/149
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
15Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
10Investigating individual particles
14Electro-optical investigation, e.g. flow cytometers
149Sorting the particles
G01N 21/35
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
17Systems in which incident light is modified in accordance with the properties of the material investigated
25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
31Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
35using infra-red light
G01N 21/6458
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
63optically excited
64Fluorescence; Phosphorescence
645Specially adapted constructive features of fluorimeters
6456Spatial resolved fluorescence measurements; Imaging
6458Fluorescence microscopy
Applicants
  • CYTOSPEC [US/US]; 11 Ackerman Court Croton-on-Hudson, NY 10520, US (AllExceptUS)
  • DIEM, Max [DE/US]; US (UsOnly)
  • BARGONETTI, Jill [US/US]; US (UsOnly)
  • GOPEN, Tamara [US/US]; US (UsOnly)
  • BOYDSTON-WHITE, Susie [US/US]; US (UsOnly)
Inventors
  • DIEM, Max; US
  • BARGONETTI, Jill; US
  • GOPEN, Tamara; US
  • BOYDSTON-WHITE, Susie; US
Agents
  • HODGSON, Rodney, T.; 822 Pinesbridge Road Ossining, NY 10562, US
Priority Data
60/116,75522.01.1999US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHOD OF CHARACTERIZATION OF BIOLOGICAL ENTITIES
(FR) METHODE DE CARACTERISATION D'ENTITES BIOLOGIQUES
Abstract
(EN)
An apparatus and method are disclosed for measuring the infrared vibrational spectral characteristics of each a large number of biological entities such as cells, and from the measurements statistically determining the presence of anomalies such as cancer.
(FR)
L'invention se rapporte à un appareil et à une méthode permettant de mesurer les caractéristiques spectrales vibratoires dans l'infrarouge de chacune des entités d'une pluralité d'entités telles que des cellules, et de déterminer statistiquement à partir de ces mesures la présence d'anomalies telles qu'un cancer.
Also published as
Latest bibliographic data on file with the International Bureau