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1. WO2000043017 - COMPOSITION OF ANTI-HIV DRUGS AND ANTI-CORTISOL COMPOUNDS AND METHOD FOR DECREASING THE SIDE EFFECTS OF ANTI-HIV DRUGS IN A HUMAN

Publication Number WO/2000/043017
Publication Date 27.07.2000
International Application No. PCT/US2000/001364
International Filing Date 20.01.2000
Chapter 2 Demand Filed 17.08.2000
IPC
A61K 31/70 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
CPC
A61K 31/70
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
Y10S 514/885
YSECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
10TECHNICAL SUBJECTS COVERED BY FORMER USPC
STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
514Drug, bio-affecting and body treating compositions
885Immune response affecting drug
Y10S 514/974
YSECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
10TECHNICAL SUBJECTS COVERED BY FORMER USPC
STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
514Drug, bio-affecting and body treating compositions
974Containing designated ingredient to reduce noxious effects of active ingredient, e.g. taste masking, odor reducing
Applicants
  • STEROIDOGENESIS INHIBITORS INTERNATIONAL [US/US]; Suite 310 101 Convention Center Drive Las Vegas, NV 89109, US
Inventors
  • SAPSE, Alfred, T.; US
Agents
  • STANDLEY, Jeffrey, S. ; Standley & Gilcrest LLP Suite 210 495 Metro Place S. Dublin, OH 43017, US
Priority Data
09/234,53221.01.1999US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) COMPOSITION OF ANTI-HIV DRUGS AND ANTI-CORTISOL COMPOUNDS AND METHOD FOR DECREASING THE SIDE EFFECTS OF ANTI-HIV DRUGS IN A HUMAN
(FR) COMPOSITION DE MEDICAMENTS ANTI-VIH, COMPOSES ANTI-CORTISOL, ET PROCEDE DE DIMINUTION DES EFFETS SECONDAIRES DES MEDICAMENTS ANTI-VIH CHEZ L'HOMME
Abstract
(EN)
The present invention is based, in part, upon the discovery that the use of an anti-HIV drug in combination with at least one cortisol blocker such as procaine, reduces the side effects associated with anti-HIV drugs. The invention also relates to a method of treating the high cortisol catabolic effects of diseases such as AIDS in the HIV positive population and those with AIDS related complexes by the administration of a cortisol blocker. The present invention also discloses a composition comprising an anti-HIV drug and a cortisol blocker. More specifically, the present invention relates to a cortisol blocking composition which comprises procaine, ascorbic acid and zinc heptahydrate.
(FR)
L'invention porte, en partie, sur la découverte que l'administration d'un médicament anti-VIH, combinée à celle d'au moins un agent de blocage du cortisol, tel que la procaïne, diminue les effets secondaires associés aux médicaments anti-VIH. L'invention concerne également un procédé de traitement des effets cataboliques importants du cortisol, dans des maladies telles que le SIDA, chez la population séropositive et chez ceux souffrant de complexes associés au SIDA, ce procédé consistant à administrer un agent de blocage du cortisol. L'invention concerne encore une composition comprenant un médicament anti-VIH ainsi qu'un agent de blocage du cortisol, et notamment une composition, à base d'un agent de blocage du cortisol, comprenant de la procaïne, de l'acide ascorbique et de l'heptahydrate de zinc.
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