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1. WO2000042996 - USE OF ANTICONVULSANT DERIVATIVES FOR TREATING CLUSTER HEADACHES

Publication Number WO/2000/042996
Publication Date 27.07.2000
International Application No. PCT/US2000/000919
International Filing Date 13.01.2000
Chapter 2 Demand Filed 10.08.2000
IPC
A61K 31/255 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
21Esters, e.g. nitroglycerine, selenocyanates
255of sulfoxy acids or sulfur analogues thereof
A61K 31/35 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
335having oxygen as the only ring hetero atom, e.g. fungichromin
35having six-membered rings with one oxygen as the only ring hetero atom
CPC
A61K 31/255
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
21Esters, e.g. nitroglycerine, selenocyanates
255of sulfoxy acids or sulfur analogues thereof
A61K 31/35
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
335having oxygen as the only ring hetero atom, e.g. fungichromin
35having six-membered rings with one oxygen as the only ring hetero atom
A61K 31/7048
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
7042Compounds having saccharide radicals and heterocyclic rings
7048having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin ; digitoxin or digoxin
Applicants
  • ORTHO-MCNEIL PHARMACEUTICAL, INC. [US/US]; U.S. Route 202 Raritan, NJ 08869-0602, US (AllExceptUS)
  • CARRAZANA, Enrique [US/US]; US (UsOnly)
  • WHEELER, Steve, D. [US/US]; US (UsOnly)
Inventors
  • CARRAZANA, Enrique; US
  • WHEELER, Steve, D.; US
Agents
  • CIAMPORCERO, Audley, A., Jr. ; Johnson and Johnson One Johnson Plaza New Brunswick, NJ 08903-7003, US
Priority Data
60/116,38819.01.1999US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) USE OF ANTICONVULSANT DERIVATIVES FOR TREATING CLUSTER HEADACHES
(FR) DERIVES ANTI-CONVULSIFS PERMETTANT DE TRAITER LES CEPHALEES VASCULAIRES DE HORTON
Abstract
(EN)
The use of anticonvulsant derivatives of formula (I) treating cluster headaches is disclosed. Wherein X is CH2 or oxygen; R1 is hydrogen of C1-C4 alkyl; and R2, R3, R4 and R5 are independently hydrogen or C1-C3 alkyl and, when X is CH2, R4 and R5 may be alkene groups joined to form a benzene ring and, when X is oxygen, R2 and R3 and/or R4 and R5 together may be a methylenedioxy group of the following formula (II): wherein R6 and R7 are the same or different and are hydrogen, C1-C¿3 alkyl or R6 and R7 together with the carbon to which they are attached are joined to form a cyclopentyl or cyclohexyl ring.
(FR)
La présente invention concerne des dérivés anti-convulsifs permettant de traiter les céphalées vasculaires de Horton.
Also published as
CZPV2001-2620
NO20013554
NZ513115
TR2001/02711
ZA200106786
Other related publications
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