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1. WO2000042069 - BONE STIMULATING FACTOR

Publication Number WO/2000/042069
Publication Date 20.07.2000
International Application No. PCT/CA2000/000031
International Filing Date 13.01.2000
Chapter 2 Demand Filed 11.08.2000
IPC
A61K 38/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
C07K 14/51 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
475Growth factors; Growth regulators
51Bone morphogenic factor; Osteogenin; Osteogenic factor; Bone-inducing factor
CPC
A61K 38/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
A61P 19/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
19Drugs for skeletal disorders
A61P 19/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
19Drugs for skeletal disorders
08for bone diseases, e.g. rachitism, Paget's disease
10for osteoporosis
C07K 14/51
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
475Growth factors; Growth regulators
51Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
C07K 14/52
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
52Cytokines; Lymphokines; Interferons
C07K 7/06
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
7Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
04Linear peptides containing only normal peptide links
06having 5 to 11 amino acids
Applicants
  • OSTEOPHARM INC. [CA/CA]; Unit 14 1155 North Service Road West Oakville, Ontario L6M 3E3, CA (AllExceptUS)
  • TAM, Cherk, Shing [CA/CA]; CA (UsOnly)
Inventors
  • TAM, Cherk, Shing; CA
Agents
  • HUNT, John, C. ; Blake, Cassels & Graydon LLP Box 25 Commerce Court West Toronto, Ontario M5L 1A9, CA
  • VOSSIUS & PARTNER; Postfach 86 07 67 D-81634 München, DE
Priority Data
09/229,30413.01.1999US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) BONE STIMULATING FACTOR
(FR) FACTEUR DE STIMULATION DE LA CROISSANCE OSSEUSE
Abstract
(EN)
Polypeptides which increase or promote mammalian bone growth, related nucleotide sequences, antibodies, diagnostic kits and treatments. Subsequences of the polypeptide Ile Lys Thr Thr Ser Gly Ile His Pro Lys Asn Ile Glu Ser have been shown to promote growth. Subsequences include Thr Thr Ser Gly Ile His Pro Lys.
(FR)
L'invention concerne des polypeptides augmentant ou favorisant la croissance osseuse chez les mammifères, ainsi que des séquences de nucléotides, des anticorps, des trousses de diagnostic et des traitements qui y sont associés. Des sous-séquences du polypeptide Ile Lys Thr Thr Ser Gly Ile His Pro Lys Asn Ile Glu Ser se sont avérées favoriser cette croissance. Lesdites sous-séquences comprennent Thr Thr Ser Gly Ile His Pro Lys.
Also published as
CZPV2001-2456
GE5968/1
HRP20010511A
ININ/PCT/2001/00560/DEL
IS5999
NO20013257
NZ512637
YUP-497/01
ZA200105734
Latest bibliographic data on file with the International Bureau