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1. WO2000042060 - BIS-AMINO ACID SULFONAMIDES CONTAINING N-TERMINALLY A SUBSTITUTED BENZYL GROUP AS HIV PROTEASE INHIBITORS

Publication Number WO/2000/042060
Publication Date 20.07.2000
International Application No. PCT/US2000/000820
International Filing Date 13.01.2000
Chapter 2 Demand Filed 27.07.2000
IPC
A61K 38/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
C07K 5/06 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
5Peptides having up to four amino acids in a fully defined sequence; Derivatives thereof
04containing only normal peptide links
06Dipeptides
CPC
A61K 38/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
C07K 5/06026
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
5Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
04containing only normal peptide links
06Dipeptides
06008with the first amino acid being neutral
06017and aliphatic
06026the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
C07K 5/06191
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
5Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
04containing only normal peptide links
06Dipeptides
06191containing heteroatoms different from O, S, or N
Applicants
  • DUPONT PHARMACEUTICALS COMPANY [US/US]; Chestnut Run Plaza 974 Centre Road Wilmington, DE 19805, US
Inventors
  • KALTENBACH, Robert, F.; US
  • TRAINOR, George, L.; US
Agents
  • FERGUSON, Blair, Q.; Dupont Pharmaceuticals Company Legal Patent Records Center 1007 Market Street Wilmington, DE 19898, US
Priority Data
60/115,74613.01.1999US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) BIS-AMINO ACID SULFONAMIDES CONTAINING N-TERMINALLY A SUBSTITUTED BENZYL GROUP AS HIV PROTEASE INHIBITORS
(FR) BIS-AMINOACIDES SULFAMIDES CONTENANT UN GROUPE BENZYLE SUBSTITUE A L'EXTREMITE N-TERMINALE UTILISES COMME INHIBITEURS DE LA PROTEASE DU VIH
Abstract
(EN)
This invention relates generally to bis-amino acid sulfonamides containing substituted benzyl amines of formula (I) or stereoisomeric forms, stereoisomeric mixtures, or pharmaceutically acceptable salt forms thereof, which are useful as HIV protease inhibitors, pharmaceutical compositions and diagnostic kits comprising the same, methods of using the same for treating viral infection or as assay standards or reagents, and intermediates and processes for making the same.
(FR)
La présente invention concerne, de manière générale, des bis-aminoacides sulfamides renfermant des benzylamines substituées de formule 1, ou des formes ou des mélanges stéréoisomères de ceux-ci ou leurs formes de sels pharmaceutiquement acceptables, lesquels composés sont utilisés comme inhibiteurs de la protéase du VIH. L'invention concerne également des compositions pharmaceutiques et des trousses de diagnostic les comprenant, des procédés d'utilisation de celles-ci dans le traitement d'infections virales ou comme étalons ou réactifs de bioanalyse, ainsi que leurs intermédiaires et procédés de fabrication.
Also published as
CZPV2001-2435
ININ/PCT/2001/00723/MUM
NO20013338
NZ512151
SK200100952
SK9522001
TR2001/02033
US09980529
ZA200104499
Other related publications
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