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1. WO2000042053 - DERIVATIVES OF MONOSACCHARIDES AS CELL ADHESION INHIBITORS

Publication Number WO/2000/042053
Publication Date 20.07.2000
International Application No. PCT/IB2000/000021
International Filing Date 10.01.2000
Chapter 2 Demand Filed 09.08.2000
IPC
C07H 9/04 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
9Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
02the hetero ring containing only oxygen as ring hetero atoms
04Cyclic acetals
C07H 13/12 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
13Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
12by acids having the group -X-C (=X)-X-, or halides thereof, in which X means nitrogen, oxygen, sulfur, selenium, or tellurium, e.g. carbonic acid, carbamic acid
CPC
A61P 11/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
06Antiasthmatics
A61P 17/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
17Drugs for dermatological disorders
06Antipsoriatics
A61P 19/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
19Drugs for skeletal disorders
02for joint disorders, e.g. arthritis, arthrosis
C07H 13/12
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
13Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
12by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid
C07H 15/00
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
15Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
C07H 9/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
9Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
02the hetero ring containing only oxygen as ring hetero atoms
04Cyclic acetals
Applicants
  • RANBAXY LABORATORIES LIMITED [IN/IN]; 19 Nehru Place New Delhi 110 019, IN (AllExceptUS)
  • ARORA, Sudershan, K. [IN/IN]; IN (UsOnly)
  • TANWAR, Madan, P. [IN/IN]; IN (UsOnly)
  • GUPTA, Jang, Bahadur [IN/IN]; IN (UsOnly)
  • SHARMA, Geeta [IN/IN]; IN (UsOnly)
Inventors
  • ARORA, Sudershan, K.; IN
  • TANWAR, Madan, P.; IN
  • GUPTA, Jang, Bahadur; IN
  • SHARMA, Geeta; IN
Priority Data
09/229,15512.01.1999US
09/411,35701.10.1999US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) DERIVATIVES OF MONOSACCHARIDES AS CELL ADHESION INHIBITORS
(FR) DERIVES DE MONOSACCHARIDES EN TANT QU'INHIBITEURS DE L'ADHESION CELLULAIRE
Abstract
(EN)
The present application relates to a group of novel substituted pentose and hexose monosaccharide derivatives, not previously disclosed, which exhibit potent anti-cell adhesion and anti-inflammatory activities. Methods of preparation, pharmaceutical compositions containing the compounds and methods of treatment, suppression and prevention of cell adhesion mediated chronic inflammatory disorders are also described.
(FR)
La présente invention concerne un groupe de nouveaux dérivés de pentose ou d'hexose substitués, non divulgués auparavant, possédant de puissantes activités d'anti-adhésion cellulaire et anti-inflammatoires. L'invention concerne également des procédé de préparation, des compositions pharmaceutiques contenant ces composés et des traitements, ainsi que l'élimination et la prévention de troubles inflammatoires chroniques induits par adhésion cellulaire.
Also published as
CRCR2001-006422
CZPV2001-2541
HRP20010527A
NZ512851
SK200100996
SK9962001
TR2001/02031
YUP-501/01
Latest bibliographic data on file with the International Bureau