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1. WO2000042045 - FUNCTIONALIZED HETEROCYCLES AS CHEMOKINE RECEPTOR MODULATORS

Publication Number WO/2000/042045
Publication Date 20.07.2000
International Application No. PCT/US1999/030434
International Filing Date 20.12.1999
Chapter 2 Demand Filed 20.07.2000
IPC
C07D 455/02 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
455Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo quinolizines, e.g. berberine
02containing not further condensed quinolizine ring systems
C07D 491/14 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
491Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/-C07D459/290
12in which the condensed system contains three hetero rings
14Ortho-condensed systems
C07D 491/22 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
491Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/-C07D459/290
22in which the condensed system contains four or more hetero rings
CPC
C07D 455/02
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
455Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
02containing not further condensed quinolizine ring systems
C07D 491/14
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
491Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
12in which the condensed system contains three hetero rings
14Ortho-condensed systems
Applicants
  • WARNER-LAMBERT COMPANY [US/US]; 201 Tabor Road Morris Plains, NJ 07950, US (AllExceptUS)
  • HARRIMAN, Geraldine, C. [US/US]; US (UsOnly)
  • KOLZ, Christine, Nylund [US/US]; US (UsOnly)
  • LULY, Jay, R. [US/US]; US (UsOnly)
  • ROTH, Bruce, David [US/US]; US (UsOnly)
  • SONG, Yuntao [CN/US]; US (UsOnly)
  • TRIVEDI, Bharat, Kalidas [IN/US]; US (UsOnly)
Inventors
  • HARRIMAN, Geraldine, C.; US
  • KOLZ, Christine, Nylund; US
  • LULY, Jay, R.; US
  • ROTH, Bruce, David; US
  • SONG, Yuntao; US
  • TRIVEDI, Bharat, Kalidas; US
Agents
  • RYAN, M., Andrea; Warner-Lambert Company 201 Tabor Road Morris Plains, NJ 07950 , US
  • MANSMANN, Ivo Dr. Rudolf Tesch; Warner-Lambert Company Legal Division Patent Department Gödecke AG Mooswaldallee D-79090 Freiburg, DE
Priority Data
60/115,65413.01.1999US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) FUNCTIONALIZED HETEROCYCLES AS CHEMOKINE RECEPTOR MODULATORS
(FR) HETEROCYCLES FONCTIONNALISES EN TANT QUE MODULATEURS DES RECEPTEURS DE CHIMIOKINES
Abstract
(EN)
The present invention is a novel series of functionalized heterocycles as chemokine receptor modulators of Formula (I) useful as modulators of chemokine receptor activity. The compounds are useful in the treatment and prevention of the AIDS virus. Intermediates useful in the prepartion of the final products, pharmaceutical compositions containing the final products are also taught.
(FR)
L'invention concerne une nouvelle série d'hétérocycles fonctionnalisés en tant que modulateurs des récepteurs de chimiokines de formule (I) [cycle fermé] [cycle ouvert], qui conviennent comme modulateurs de l'activité des récepteurs de chimiokines. Les composés servent à traiter et à prévenir le virus du SIDA. Des intermédiaires servent dans la préparation des produits finals. L'invention traite également de compositions pharmaceutiques contenant lesdits produits finals.
Also published as
CZPV2001-2502
ININ/PCT/2001/1088/CHE
NO20013456
NZ513435
ROa 2001 00806
SK200100997
SK9972001
US09889315
ZA200106592
Latest bibliographic data on file with the International Bureau