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1. WO2000042018 - POLYSUBSTITUTED 6-PHENYLPHENANTHRIDINES WITH PDE-IV INHIBITING ACTIVITY

Publication Number WO/2000/042018
Publication Date 20.07.2000
International Application No. PCT/EP2000/000151
International Filing Date 12.01.2000
Chapter 2 Demand Filed 18.07.2000
IPC
C07D 221/12 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
221Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/-C07D219/187
02condensed with carbocyclic rings or ring systems
04Ortho- or peri-condensed ring systems
06Ring systems of three rings
10Aza-phenanthrenes
12Phenanthridines
CPC
A61P 1/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
A61P 1/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
04for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
A61P 11/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
A61P 11/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
06Antiasthmatics
A61P 11/08
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
08Bronchodilators
A61P 13/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
13Drugs for disorders of the urinary system
02of urine or of the urinary tract, e.g. urine acidifiers
Applicants
  • BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH [DE/DE]; Byk-Gulden-Str. 2 D-78467 Konstanz, DE (AllExceptUS)
  • GUTTERER, Beate [DE/DE]; DE (UsOnly)
Inventors
  • GUTTERER, Beate; DE
  • FLOCKERZI, Dieter; DE
  • AMSCHLER, Hermann; null
  • GRUNDLER, Gerhard; DE
  • HATZELMANN, Armin; DE
  • BUNDSCHUH, Daniela; DE
  • BEUME, Rolf; DE
  • BOSS, Hildegard; DE
  • KLEY, Hans-Peter; DE
Common Representative
  • BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH; Byk-Gulden-Str. 2 D-78467 Konstanz, DE
Priority Data
99100696.615.01.1999EP
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) POLYSUBSTITUTED 6-PHENYLPHENANTHRIDINES WITH PDE-IV INHIBITING ACTIVITY
(FR) 6-PHENYLPHENANTHRIDINES POLYSUBSTITUES A ACTIVITE INHIBANT PDE-IV
Abstract
(EN)
Compounds of formula (I), in which R1, R2, R3, R31, R4, R5, R51 and R6 have the meanings indicated in the description, are novel active bronchial therapeutics.
(FR)
L'invention concerne des composés représentés par la formule (I). Dans cette formule R1, R2, R3, R31, R4, R5, R51 et R6 sont tels que spécifiés dans les spécifications. Ces composés sont de nouvelles substances bronchiques actives.
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