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1. WO2000042017 - PHENANTHRIDINE-N-OXIDES WITH PDE-IV INHIBITING ACTIVITY

Publication Number WO/2000/042017
Publication Date 20.07.2000
International Application No. PCT/EP2000/000150
International Filing Date 12.01.2000
Chapter 2 Demand Filed 18.07.2000
IPC
C07D 221/12 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
221Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/-C07D219/187
02condensed with carbocyclic rings or ring systems
04Ortho- or peri-condensed ring systems
06Ring systems of three rings
10Aza-phenanthrenes
12Phenanthridines
CPC
A61P 11/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
04for throat disorders
A61P 11/08
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
08Bronchodilators
C07D 221/12
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
221Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
02condensed with carbocyclic rings or ring systems
04Ortho- or peri-condensed ring systems
06Ring systems of three rings
10Aza-phenanthrenes
12Phenanthridines
Applicants
  • BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH [DE/DE]; Byk-Gulden-Str. 2 D-78467 Konstanz, DE (AllExceptUS)
  • GUTTERER, Beate [DE/DE]; DE (UsOnly)
Inventors
  • GUTTERER, Beate; DE
  • FLOCKERZI, Dieter; DE
  • AMSCHLER, Hermann; null
  • HATZELMANN, Armin; DE
  • BUNDSCHUH, Daniela; DE
  • BEUME, Rolf; DE
  • BOSS, Hildegard; DE
  • KLEY, Hans-Peter; DE
Common Representative
  • BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH; Byk-Gulden-Str. 2 D-78467 Konstanz, DE
Priority Data
99100707.115.01.1999EP
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) PHENANTHRIDINE-N-OXIDES WITH PDE-IV INHIBITING ACTIVITY
(FR) PHENANTHRIDINE-N-OXYDES A ACTIVITE INHIBANT PDE-IV
Abstract
(EN)
The N-oxides of the compounds of formula (I), in which R1, R2, R3, R31, R4, R5, R51 and R6 have the meanings indicated in the description, are novel active bronchial therapeutics.
(FR)
L'invention concerne les N-oxides des composés représentés par la formule (I). Dans cette formule, R1, R2, R3, R31, R4, R5, R51 et R6 sont tels que décrits dans les spécifications. Ces composés sont des substances thérapeutiques bronchiques actives.
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