Processing

Please wait...

Settings

Settings

1. WO2000042014 - 1-(6- METHYLPYRIDINE- 3-YL)-2-[4- (METHYLSULFONYL) PHENYL] ETHANONE AND METHOD FOR ITS PREPARATION

Publication Number WO/2000/042014
Publication Date 20.07.2000
International Application No. PCT/EP2000/000240
International Filing Date 13.01.2000
Chapter 2 Demand Filed 14.07.2000
IPC
C07D 213/50 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
213Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
02having three double bonds between ring members or between ring members and non-ring members
04having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
24with substituted hydrocarbon radicals attached to ring carbon atoms
44Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
46Oxygen atoms
50Ketonic radicals
C07D 213/57 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
213Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
02having three double bonds between ring members or between ring members and non-ring members
04having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
24with substituted hydrocarbon radicals attached to ring carbon atoms
54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
57Nitriles
CPC
C07D 213/50
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
213Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
02having three double bonds between ring members or between ring members and non-ring members
04having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
24with substituted hydrocarbon radicals attached to ring carbon atoms
44Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
46Oxygen atoms
50Ketonic radicals
C07D 213/57
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
213Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
02having three double bonds between ring members or between ring members and non-ring members
04having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
24with substituted hydrocarbon radicals attached to ring carbon atoms
54Radicals substituted by carbon atoms having three bonds to heteroatoms, with at the most one to halogen, e.g. ester or nitrile radicals
57Nitriles
Applicants
  • LONZA AG [CH/CH]; Münchensteinerstrasse 38 CH-4052 Basel, CH (AllExceptUS)
  • MERCK & CO., INC. [US/US]; 126 Lincoln Avenue Rahway, NJ 07065-0907, US (AllExceptUS)
  • ARMBRUSTER, Erich [CH/CH]; CH (UsOnly)
  • BESSARD, Yves [CH/CH]; CH (UsOnly)
  • KUO, David [CA/US]; US (UsOnly)
  • LERESCHE, James, Edward [CH/CH]; CH (UsOnly)
  • PROPLESCH, Ralf [DE/CH]; CH (UsOnly)
  • RODUIT, Jean-Paul [CH/CH]; CH (UsOnly)
Inventors
  • ARMBRUSTER, Erich; CH
  • BESSARD, Yves; CH
  • KUO, David; US
  • LERESCHE, James, Edward; CH
  • PROPLESCH, Ralf; CH
  • RODUIT, Jean-Paul; CH
Agents
  • RITTHALER, Wolfgang ; Winter, Brandl & Partner Alois-Steinecker-Strasse 22 D-85354 Freising, DE
Priority Data
60/145,99629.07.1999US
99100590.114.01.1999EP
Publication Language German (DE)
Filing Language German (DE)
Designated States
Title
(DE) 1-(6-METHYLPYRIDIN-3-YL)-2-((4-(METHYLSULFONYL)PHENYL)ETHANON UND VERFAHREN ZU SEINER HERSTELLUNG
(EN) 1-(6- METHYLPYRIDINE- 3-YL)-2-[4- (METHYLSULFONYL) PHENYL] ETHANONE AND METHOD FOR ITS PREPARATION
(FR) 1-(6- METHYLPYRIDIN- 3-YL)-2-[4- (METHYLSULFONYL) PHENYL] ETHANONE ET SON PROCEDE DE PRODUCTION
Abstract
(DE)
Es wird ein neues Ausgangsprodukt zur Herstellung von COX-2-Inhibitoren, die Verbindung 1-(6- Methylpyridin- 3-yl)-2-[4- (methylsulfonyl) phenyl]ethanon der Formel (I) sowie ein Verfahren zu dessen Herstellung beschrieben.
(EN)
The invention relates to a new starting product for the preparation of COX-2 inhibitors, notably the compound 1-(6- methylpyridine- 3-yl)-2-[(4- (methylsulfonyl) phenyl] ethanone of the formula (I), and to a method for producing same.
(FR)
L'invention concerne un nouveau produit de départ pour la production d'inhibiteurs de COX-2, à savoir le composé suivant: 1-(6- méthylpyridin- 3-yl)-2-[4- (méthylsulfonyl) phényl] éthanone de formule (I), ainsi qu'un procédé pour sa production.
Other related publications
Latest bibliographic data on file with the International Bureau