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1. WO2000041768 - PATIENT PORTABLE DEVICE FOR PHOTODYNAMIC THERAPY

Publication Number WO/2000/041768
Publication Date 20.07.2000
International Application No. PCT/US2000/000805
International Filing Date 14.01.2000
Chapter 2 Demand Filed 16.08.2000
IPC
A61B 18/22 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
18Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
18by applying electromagnetic radiation, e.g. microwaves
20using laser
22the beam being directed along or through a flexible conduit, e.g. an optical fibre; Hand-pieces therefor
A61B 18/24 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
18Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
18by applying electromagnetic radiation, e.g. microwaves
20using laser
22the beam being directed along or through a flexible conduit, e.g. an optical fibre; Hand-pieces therefor
24with a catheter
A61N 5/06 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
5Radiation therapy
06using light
CPC
A61B 2018/2005
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
18Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
18by applying electromagnetic radiation, e.g. microwaves
20using laser
2005with beam delivery through an interstitially insertable device, e.g. needle
A61B 2018/2261
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
18Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
18by applying electromagnetic radiation, e.g. microwaves
20using laser
22the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or; hand-pieces therefor
2255Optical elements at the distal end of probe tips
2261with scattering, diffusion or dispersion of light
A61N 2005/0645
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
5Radiation therapy
06using light
0635characterised by the body area to be irradiated
0643Applicators, probes irradiating specific body areas in close proximity
0645Applicators worn by the patient
A61N 5/0601
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
5Radiation therapy
06using light
0601Apparatus for use inside the body
A61N 5/062
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
5Radiation therapy
06using light
0613Apparatus adapted for a specific treatment
062Photodynamic therapy, i.e. excitation of an agent
Applicants
  • LIGHT SCIENCES CORPORATION [US/US]; No. E-5 1065 12 Avenue, N.W. Issaquah, WA 98027, US (AllExceptUS)
  • CHEN, James [US/US]; US (UsOnly)
  • WILKERSON, Brian [IL/US]; US (UsOnly)
  • BROWN, Dave [US/US]; US (UsOnly)
  • HUSTON, Darrin [US/US]; US (UsOnly)
  • MCQUADE, Mike [US/US]; US (UsOnly)
Inventors
  • CHEN, James; US
  • WILKERSON, Brian; US
  • BROWN, Dave; US
  • HUSTON, Darrin; US
  • MCQUADE, Mike; US
Agents
  • MAYS, Thomas, D. ; Morrison & Foerster LLP 2000 Pennsylvania Avenue, N.W. Washington, DC 20006-1888, US
  • NICHOLLS, Michael, John ; J.A. Kemp & Co. 14 South Square Gray's Inn London WC1R 5LX, GB
Priority Data
09/232,12915.01.1999US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) PATIENT PORTABLE DEVICE FOR PHOTODYNAMIC THERAPY
(FR) APPAREIL PORTATIF DE THERAPIE PHOTODYNAMIQUE DESTINE A UN PATIENT
Abstract
(EN)
A patient portable photodynamic therapy device securable to a patient includes a lightweight rechargeable battery and a light source, such as an LED or a cold cathode fluorescent (CCF) tube powered thereby. The light source is coupled in light channeling relation to a proximal portion of a biocompatible optical fiber, which includes a distal portion with an optional diffuser that uniformly distributes light as it exits the distal portion. The light channeling between the light source and an optical fiber may be accomplished through any number of lens, including a totally internally reflective (TIR) lens. The distal end of the optical fiber is optionally provided with an anchoring balloon that can be inflated after the optical fiber is properly positioned at a treatment site within a patient's body. The balloon securely lodges the distal portion within the tissue at the treatment site, and is deflated to facilitate the removal of the optical fiber once the treatment is complete.
(FR)
Un appareil portatif de thérapie photodynamique pour patient pouvant être fixé sur ce dernier comprend un accumulateur rechargeable léger et une source de lumière, telle qu'une DEL ou un tube fluorescent à cathode froide alimenté par ce dernier. La source de lumière est couplée de manière à propager la lumière, à une partie proximale d'une fibre optique biocompatible qui comporte elle-même une partie distale dotée d'un diffuseur facultatif qui distribue uniformément la lumière à sa sortie de la partie distale. La propagation de la lumière entre la source de lumière et la fibre optique peut être réalisée au moyen d'un nombre quelconque de lentilles, y compris une lentille à réflexion totale interne. L'extrémité distale de la fibre optique est facultativement équipée d'un ballonnet d'ancrage qui peut être gonflé après la mise en place correcte de la fibre optique au niveau d'un site de traitement à l'intérieur du corps d'un patient. Le ballonnet abrite en toute sécurité la partie distale à l'intérieur des tissus au niveau du site de traitement, puis, lorsque le traitement est terminé, on le dégonfle pour faciliter le retrait de la fibre optique.
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