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1. WO2000041730 - A COMPOSITION AND METHOD FOR THE ENHANCEMENT OF THE EFFICACY OF DRUGS

Publication Number WO/2000/041730
Publication Date 20.07.2000
International Application No. PCT/AU2000/000004
International Filing Date 06.01.2000
Chapter 2 Demand Filed 14.07.2000
IPC
A61K 45/06 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
A61K 47/36 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
CPC
A61K 31/728
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
726Glycosaminoglycans, i.e. mucopolysaccharides
728Hyaluronic acid
A61K 45/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
A61K 47/36
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
A61K 9/0019
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
0012Galenical forms characterised by the site of application
0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
Applicants
  • MEDITECH RESEARCH LIMITED [AU/AU]; Level 1 Sterling House 8 Parliament Place West Perth, W.A. 6005, AU (AllExceptUS)
  • BROWN, Tracey [AU/AU]; AU (UsOnly)
Inventors
  • BROWN, Tracey; AU
Agents
  • GRIFFITH HACK; Level 3 509 St Kilda Road Melbourne, VIC 3004, AU
Priority Data
PP 813113.01.1999AU
PQ 393809.11.1999AU
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) A COMPOSITION AND METHOD FOR THE ENHANCEMENT OF THE EFFICACY OF DRUGS
(FR) COMPOSITION VISANT A ACCROITRE L'EFFICACITE DE MEDICAMENTS ET METHODES AFFERENTES
Abstract
(EN)
The present invention relates to the enhancement of the efficacy of drugs, and more particularly, with overcoming the resistance of cells or organisms to drugs. In particular, the present invention provides a method for enhancing the effectiveness of a cytotoxic or anti-neoplastic agent, comprising the step of co-administering said agent with hyaluronan, wherein co-administration with hyaluronan enhances the agent's cancer cell-killing potential.
(FR)
Cette invention, qui a trait à l'accroissement de l'efficacité de médicaments, vise plus précisément à surmonter la pharmacorésistance de cellules ou d'organismes. Elle porte, notamment, sur une méthode permettant d'accroître l'efficacité d'un agent cytotoxique ou anti-néoplasique, laquelle méthode consiste à administrer cet agent en association avec du hyaluronan. Administré de concert avec cet agent, le hyaluronan renforce son potentiel de tueur de cellules cancéreuses.
Also published as
ININ/PCT/2001/765/KOL
NZ512676
US09889203
ZA200105492
Latest bibliographic data on file with the International Bureau