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1. WO2000041695 - UTILIZATION OF PYRIMIDINE DERIVATIVES FOR PREVENTING AND TREATING CEREBRAL ISCHAEMIA

Publication Number WO/2000/041695
Publication Date 20.07.2000
International Application No. PCT/EP1999/010369
International Filing Date 24.12.1999
Chapter 2 Demand Filed 13.05.2000
IPC
A61K 31/505 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
CPC
A61K 31/505
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495having six-membered rings with two ; or more; nitrogen atoms as the only ring heteroatoms, e.g. piperazine ; or tetrazines
505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
Applicants
  • BASF AKTIENGESELLSCHAFT [DE/DE]; D-67056 Ludwigshafen, DE (AllExceptUS)
  • STEINER, Gerd [DE/DE]; DE (UsOnly)
  • SCHELLHAAS, Kurt [DE/DE]; DE (UsOnly)
  • LUBISCH, Wilfried [DE/DE]; DE (UsOnly)
  • HOLZENKAMP, Uta [DE/DE]; DE (UsOnly)
  • STARCK, Dorothea [DE/DE]; DE (UsOnly)
  • KNOPP, Monika [DE/DE]; DE (UsOnly)
  • SZABO, Laszlo [DE/DE]; DE (UsOnly)
  • EMLING, Franz [DE/DE]; DE (UsOnly)
  • GARCIA-LADONA, Francisco Javier [ES/DE]; DE (UsOnly)
  • HOFMANN, Hans-Peter [DE/DE]; DE (UsOnly)
  • UNGER, Liliane [DE/DE]; DE (UsOnly)
Inventors
  • STEINER, Gerd; DE
  • SCHELLHAAS, Kurt; DE
  • LUBISCH, Wilfried; DE
  • HOLZENKAMP, Uta; DE
  • STARCK, Dorothea; DE
  • KNOPP, Monika; DE
  • SZABO, Laszlo; DE
  • EMLING, Franz; DE
  • GARCIA-LADONA, Francisco Javier; DE
  • HOFMANN, Hans-Peter; DE
  • UNGER, Liliane; DE
Common Representative
  • BASF AKTIENGESELLSCHAFT; D-67056 Ludwigshafen, DE
Priority Data
199 00 545.111.01.1999DE
Publication Language German (DE)
Filing Language German (DE)
Designated States
Title
(DE) VERWENDUNG VON PYRIMIDINDERIVATEN ZUR PROPHYLAXE UND THERAPIE DER ZEREBRALEN ISCHÄMIE
(EN) UTILIZATION OF PYRIMIDINE DERIVATIVES FOR PREVENTING AND TREATING CEREBRAL ISCHAEMIA
(FR) UTILISATION DE DERIVES DE PYRIMIDINE POUR ASSURER LA PROPHYLAXIE ET LA THERAPIE DE L'ISCHEMIE CEREBRALE
Abstract
(DE)
Verwendung von Pyrimidin-Derivaten der Formel (I), worin die Substituenten die in der Beschreibung wiedergegebene Bedeutung besitzen, sowie deren physiologisch verträgliche Salze, zur Herstellung von Medikamenten zur Prophylaxe und Behandlung von zerebraler Ischämie und Schlaganfall.
(EN)
The invention relates to the utilization of pyrimidine derivatives of formula (I), wherein the substituents have the meaning cited in the description, and to the utilization of the physiologically compatible salts thereof for producing medicaments used for preventing and treating cerebral ischaemia and strokes.
(FR)
L'invention concerne l'utilisation de dérivés de pyrimidine de la formule (I) dans laquelle les substituants ont la signification mentionnée dans la description, ainsi que leur sels physiologiquement tolérables pour préparer des médicaments pour assurer la prophylaxie et le traitement de l'ischémie cérébrale et de l'apoplexie cérébrale.
Also published as
CZPV2001-2485
HRP20010593A
ININ/PCT/2001/954/CHE
NO20013409
SK200100969
TR2001/02008
ZA200105475
Latest bibliographic data on file with the International Bureau