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1. WO2000040972 - NMR SPECTROSCOPY METHOD

Publication Number WO/2000/040972
Publication Date 13.07.2000
International Application No. PCT/GB1999/004395
International Filing Date 23.12.1999
Chapter 2 Demand Filed 19.07.2000
IPC
C12Q 1/68 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
G01N 33/58 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
58involving labelled substances
G01R 33/465 2006.01
GPHYSICS
01MEASURING; TESTING
RMEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
33Arrangements or instruments for measuring magnetic variables
20involving magnetic resonance
44using nuclear magnetic resonance
46NMR spectroscopy
465applied to biological material, e.g. in vitro testing
CPC
C12Q 1/6816
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms
68involving nucleic acids
6813Hybridisation assays
6816characterised by the detection means
G01N 33/58
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
58involving labelled substances
G01R 33/465
GPHYSICS
01MEASURING; TESTING
RMEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
33Arrangements or instruments for measuring magnetic variables
20involving magnetic resonance
44using nuclear magnetic resonance [NMR]
46NMR spectroscopy
465applied to biological material, e.g. in vitro testing
Applicants
  • NYCOMED AMERSHAM PLC [GB/GB]; Amersham Laboratories White Lion Road Amersham Bucks HP7 9LL, GB (AllExceptUS)
  • KNOX, Peter [GB/GB]; GB (UsOnly)
  • COOK, Neil [GB/GB]; GB (UsOnly)
Inventors
  • KNOX, Peter; GB
  • COOK, Neil; GB
Agents
  • ROLLINS, Anthony, John; Nycomed Amersham plc Amersham Laboratories White Lion Road Amersham Bucks HP7 9LL, GB
Priority Data
9828853.330.12.1998GB
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) NMR SPECTROSCOPY METHOD
(FR) PROCEDE DE SPECTROSCOPIE PAR RMN
Abstract
(EN)
The invention relates to an $i(in vitro )method which comprises labelling a biological molecule with hyperpolarised xenon, and observing a magnetic resonance spectrum and/or image of the hyperpolarised xenon in the environment of the biological molecule. The spectrum/image provides information about the environment(s) at which atoms of xenon are bound to the biological molecule.
(FR)
L'invention porte sur un procédé $i(in vitro) qui consiste à marquer une molécule biologique avec un xénon hyperpolarisé et à observer un spectre à résonance magnétique et/ou une image du xénon hyperpolarisé dans l'environnement de la molécule biologique. Le spectre/image génère des informations sur l'environnement au niveau duquel des atomes de xénon sont liés à la molécule biologique.
Also published as
US09869630
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