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1. WO2000040758 - ENHANCED SEQUENCING BY HYBRIDIZATION USING POOLS OF PROBES

Publication Number WO/2000/040758
Publication Date 13.07.2000
International Application No. PCT/US2000/000458
International Filing Date 06.01.2000
Chapter 2 Demand Filed 04.08.2000
IPC
C12Q 1/68 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
CPC
C12Q 1/6874
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms
68involving nucleic acids
6869Methods for sequencing
6874involving nucleic acid arrays, e.g. sequencing by hybridisation
Applicants
  • HYSEQ INC. [US/US]; 670 Almanor Avenue Sunnyvale, CA 94086, US
Inventors
  • DRMANAC, Radoje; US
  • DRMANAC, Snezana; US
  • KITA, David; US
  • COOKE, Cory; US
  • XU, Chongjun; US
Agents
  • WILLIAMS, Joseph, A., Jr.; Marshall, 0'Toole, Gerstein, Murray & Borun 6300 Sears Tower 233 South Wacker Drive Chicago, IL 60606, US
Priority Data
60/115,28406.01.1999US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) ENHANCED SEQUENCING BY HYBRIDIZATION USING POOLS OF PROBES
(FR) SEQUENCAGE PAR HYBRIDATION, AMELIORE, UTILISANT DES GROUPES DE SONDES
Abstract
(EN)
The invention provides methods for sequencing by hybridization (SBH) using pools of probes that allow greater efficiency in conducting SBH by reducing the number of separate measurements of hybridization signals required to identify each particular nucleotide in a target nucleic acid sequence. The invention also provides pools and sets of pools of probes, as well as methods of generating pools of probes.
(FR)
L'invention concerne des techniques de séquençage par hybridation (SHB) mettant en oeuvre des groupes de sondes permettant un séquençage plus efficace en réduisant le nombre de mesures individuelles de signaux d'hybridation nécessaires à l'identification de chaque nucléotide dans une séquence d'acides nucléiques cible. L'invention concerne également des groupes et des ensembles de groupes de sondes ainsi que des procédés permettant de produire des groupes de sondes.
Also published as
Latest bibliographic data on file with the International Bureau