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1. WO2000040602 - BINDING MOLECULES FOR HUMAN FACTOR VIII AND FACTOR VIII-LIKE PROTEINS

Publication Number WO/2000/040602
Publication Date 13.07.2000
International Application No. PCT/US2000/000043
International Filing Date 03.01.2000
Chapter 2 Demand Filed 20.07.2000
IPC
C07K 7/06 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
7Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
04Linear peptides containing only normal peptide links
06having 5 to 11 amino acids
C07K 7/08 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
7Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
04Linear peptides containing only normal peptide links
08having 12 to 20 amino acids
C07K 14/00 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
CPC
C07K 14/00
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
C07K 14/001
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
001by chemical synthesis
C07K 7/06
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
7Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
04Linear peptides containing only normal peptide links
06having 5 to 11 amino acids
C07K 7/08
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
7Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
04Linear peptides containing only normal peptide links
08having 12 to 20 amino acids
Applicants
  • DYAX CORP. [US/US]; One Kendall Square Building 600, 5th floor Cambridge, MA 02139, US
Inventors
  • YU, Jinan; US
  • POTTER, M., Daniel; US
  • KELLEY, Brian, D.; US
  • DEETZ, Jeffrey, S.; US
  • BOOTH, James, E.; US
Agents
  • YANKWICH, Leon, R.; Yankwich & Associates 130 Bishop Allen Drive Cambridge, MA 02139, US
Priority Data
09/224,78504.01.1999US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) BINDING MOLECULES FOR HUMAN FACTOR VIII AND FACTOR VIII-LIKE PROTEINS
(FR) MOLECULES DE LIAISON POUR LE FACTEUR VIII HUMAIN ET PROTEINES DE TYPE FACTEUR VIII
Abstract
(EN)
Methods for detecting human factor VIII or factor VIII-like polypeptides in and isolating it from solutions such as blood or conditioned media are disclosed, together with reagents suitable for the purpose comprising binding moieties that recognize human factor VIII and/or a factor VIII-like polypeptide and form a binding complex therewith. Preferred polypeptide binding moieties are particularly disclosed.
(FR)
L'invention concerne des procédés permettant de détecter le facteur VIII humain ou des polypeptides de type facteur VIII dans des solutions telles que le sang ou un milieu conditionné et de les isoler dans ces solutions. L'invention concerne également des réactifs convenant pour ces procédés et comprenant des portions de liaison capables de reconnaître le facteur VIII humain et/ou un polypeptide de type facteur VIII et de former un complexe de liaison avec celui-ci. L'invention concerne en particulier des portions de liaison polypeptidiques préférées.
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