Processing

Please wait...

Settings

Settings

1. WO2000040557 - PROCESS FOR THE FORMATION OF INTERMEDIATES USEFUL FOR THE PREPARATION OF PHARMACEUTICALS

Publication Number WO/2000/040557
Publication Date 13.07.2000
International Application No. PCT/US2000/000313
International Filing Date 07.01.2000
Chapter 2 Demand Filed 02.08.2000
IPC
A61K 31/4745 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
47Quinolines; Isoquinolines
4738ortho- or peri-condensed with heterocyclic ring systems
4745condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenanthrolines
C07D 203/08 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
203Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
04not condensed with other rings
06having no double bonds between ring members or between ring members and non-ring members
08with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring nitrogen atom
C07D 213/30 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
213Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
02having three double bonds between ring members or between ring members and non-ring members
04having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
24with substituted hydrocarbon radicals attached to ring carbon atoms
28Radicals substituted by singly-bound oxygen or sulfur atoms
30Oxygen atoms
C07D 213/38 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
213Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
02having three double bonds between ring members or between ring members and non-ring members
04having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
24with substituted hydrocarbon radicals attached to ring carbon atoms
36Radicals substituted by singly-bound nitrogen atoms
38having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
C07D 303/08 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
303Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
02Compounds containing oxirane rings
08with hydrocarbon radicals, substituted by halogen atoms, nitro radicals or nitroso radicals
CPC
A61K 31/4745
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
47Quinolines; Isoquinolines
4738ortho- or peri-condensed with heterocyclic ring systems
4745condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
C07D 203/08
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
203Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
04not condensed with other rings
06having no double bonds between ring members or between ring members and non-ring members
08with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring nitrogen atom
C07D 213/30
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
213Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
02having three double bonds between ring members or between ring members and non-ring members
04having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
24with substituted hydrocarbon radicals attached to ring carbon atoms
28Radicals substituted by singly-bound oxygen or sulfur atoms
30Oxygen atoms
C07D 213/38
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
213Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
02having three double bonds between ring members or between ring members and non-ring members
04having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
24with substituted hydrocarbon radicals attached to ring carbon atoms
36Radicals substituted by singly-bound nitrogen atoms
38having only hydrogen, hydrocarbon radicals attached to the substituent nitrogen atom
C07D 303/08
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
303Compounds containing three-membered rings having one oxygen atom as the only ring heteroatom
02Compounds containing oxirane rings
08with hydrocarbon radicals, substituted by halogen atoms, nitro radicals or nitroso radicals
Applicants
  • VERTEX PHARMACEUTICALS INCORPORATED [US/US]; 130 Waverly Street Cambridge, MA 02139-4242, US (AllExceptUS)
  • OLIVER, Patricia, Ann [US/US]; US (UsOnly)
Inventors
  • OLIVER, Patricia, Ann; US
Agents
  • HALEY, James, F., Jr.; Fish & Neave 1251 Avenue of the Americas New York, NY 10020 , US
  • VOSSIUS & PARTNER; Siebertstrasse 4 D-81675 München, DE
Priority Data
60/115,25608.01.1999US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) PROCESS FOR THE FORMATION OF INTERMEDIATES USEFUL FOR THE PREPARATION OF PHARMACEUTICALS
(FR) PROCEDE DE FORMATION D'INTERMEDIAIRES UTILES A LA PREPARATION DE PRODUITS PHARMACEUTIQUES
Abstract
(EN)
The invention relates to a synthetic chemical process for forming an intermediate useful in manufacturing certain known nerve growth stimulatory and neuroprotective compounds and certain known multidrug resistance inhibitors.
(FR)
La présente invention concerne un procédé chimique synthétique permettant de former un intermédiaire utile à la confection de certains composés neuroprotecteurs et stimulant la croissance neuronale connus et de certains inhibiteurs de résistance à plusieurs médicaments connus
Also published as
Latest bibliographic data on file with the International Bureau